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Literature DB >> 28508204

Rearing by foster Wistar mother with high level of maternal care counteracts the development of genetic absence epilepsy and comorbid depression in WAG/Rij rats.

K Yu Sarkisova¹, A V Gabova², M A Kulikov², E A Fedosova², A B Shatskova², A A Morosov³.

Abstract

It has been shown for the first time that rearing by a foster Wistar mother with high level of maternal care (MC) counteracts the expression of genetic absence epilepsy (AE) and comorbid depression - reduces the number, duration and index of spike-wave discharges (SWDs) and immobility time in the forced swimming test, as well as exerts substantial effects on morphology and time-frequency dynamics of SWDs in WAG/Rij rats. It is supposed that increases in MC early in development might be used to counteract epileptogenesis and comorbid depression in people genetically predisposed to AE.

Entities: Chemical Disease Species

Mesh：

Year: 2017 PMID： 28508204 DOI： 10.1134/S0012496617020077

Source DB: PubMed Journal: Dokl Biol Sci ISSN： 0012-4966

13 in total

Review 1. The WAG/Rij strain: a genetic animal model of absence epilepsy with comorbidity of depression [corrected].

Authors: Karine Sarkisova; Gilles van Luijtelaar
Journal: Prog Neuropsychopharmacol Biol Psychiatry Date: 2010-11-17 Impact factor: 5.067

2. Development of hypertensive status in NISAG rats reared by normotensive Wistar rats.

Authors: G S Yakobson; A R Antonov; A L Markel'; S Y Amstislavskii; A G Taranov; M G Yakobson
Journal: Bull Exp Biol Med Date: 2001-08 Impact factor: 0.804

3. Behavioral characteristics of WAG/Rij rats susceptible and non-susceptible to audiogenic seizures.

Authors: K Yu Sarkisova; M A Kulikov
Journal: Behav Brain Res Date: 2005-09-23 Impact factor: 3.332

4. [Pup-Associated Conditioned Place Preference and Maternal Behavior in Depressive WAG/Rij Rats].

Authors: K Yu Sarkisova; K K Tanaeva; Yu V Dobryakova
Journal: Zh Vyssh Nerv Deiat Im I P Pavlova Date: 2016 Mar-Apr Impact factor: 0.437

5. [Effect of changes in the early maternal environment on predisposition to catalepsy in rats of different ages].

Authors: V G Kolpakov; T A Alekhina; N N Barykina; V F Chuguĭ; O I Petrenko; S Ia Amstislavskiĭ
Journal: Zh Vyssh Nerv Deiat Im I P Pavlova Date: 2002 Mar-Apr Impact factor: 0.437

6. Effects of mothers' prenatal psychiatric status and postnatal caregiving on infant biobehavioral regulation: can prenatal programming be modified?

Authors: Lauren A Kaplan; Lynn Evans; Catherine Monk
Journal: Early Hum Dev Date: 2007-08-30 Impact factor: 2.079

2. Effects of Postnatal Caffeine Exposure on Absence Epilepsy and Comorbid Depression: Results of a Study in WAG/Rij Rats.

Authors: Gul Ilbay; Zeynep Ikbal Dogan; Aymen Balıkcı; Seyda Erdogan; Akfer Karaoglan Kahilogulları
Journal: Brain Sci Date: 2022-03-08

2 in total

Rearing by foster Wistar mother with high level of maternal care counteracts the development of genetic absence epilepsy and comorbid depression in WAG/Rij rats.

Review 1. The WAG/Rij strain: a genetic animal model of absence epilepsy with comorbidity of depression [corrected].

2. Development of hypertensive status in NISAG rats reared by normotensive Wistar rats.

3. Behavioral characteristics of WAG/Rij rats susceptible and non-susceptible to audiogenic seizures.

4. [Pup-Associated Conditioned Place Preference and Maternal Behavior in Depressive WAG/Rij Rats].

5. [Effect of changes in the early maternal environment on predisposition to catalepsy in rats of different ages].

6. Effects of mothers' prenatal psychiatric status and postnatal caregiving on infant biobehavioral regulation: can prenatal programming be modified?

7. The impact of maternal neglect on genetic hyperactivity.

8. Swim test immobility in a genetic rat model of depression is modified by maternal environment: a cross-foster study.

9. A cross-fostering study in a genetic animal model of depression: maternal behavior and depression-like symptoms.

10. Risk of psychopathology in adolescent offspring of mothers with psychopathology and recurrent depression.

1. In Up to My Ears and Temporal Lobes: Effects of Early Life Stress on Epilepsy Development.

2. Effects of Postnatal Caffeine Exposure on Absence Epilepsy and Comorbid Depression: Results of a Study in WAG/Rij Rats.