Literature DB >> 11713551

Development of hypertensive status in NISAG rats reared by normotensive Wistar rats.

G S Yakobson1, A R Antonov, A L Markel', S Y Amstislavskii, A G Taranov, M G Yakobson.   

Abstract

Parameters of the cardiovascular system and the content of corticosterone, thyrotrophin, thyroxin, and triiodothyronine in the plasma, and norepinephrine in the myocardium were determined in male NISAG rats (hereditary stress-induced arterial hypertension) reared by normotensive Wistar rats. Cross-rearing of hypertensive rat pups by normotensive females attenuated arterial hypertension with a tendency to normalization of the examined parameters. This confirms the possibility of modifying hypertensive phenotype by changing the conditions of the early postnatal development.

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Year:  2001        PMID: 11713551     DOI: 10.1023/a:1013065508818

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

1.  Rearing by foster Wistar mother with high level of maternal care counteracts the development of genetic absence epilepsy and comorbid depression in WAG/Rij rats.

Authors:  K Yu Sarkisova; A V Gabova; M A Kulikov; E A Fedosova; A B Shatskova; A A Morosov
Journal:  Dokl Biol Sci       Date:  2017-05-16
  1 in total

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