Literature DB >> 28507379

Accuracy of frozen sections in oral cancer resections, an experience of a tertiary care hospital.

Sayed Akbar Abbas1, Mubasher Ikram2, Muhammad Usman Tariq3, Ahmed Raheem4, Javeria Saeed5.   

Abstract

The aim our study was to determine the accuracy of frozen sections in oral cancer resections. Patients who underwent oral cancer resection at Patel Hospital were included in the study. Tissues for frozen sections were obtained from the mucosal margins and tumour bed. Frozen sections were compared with the paraffin embedded sections which served as the gold standard in our study. Sensitivity, specificity, positive predictive value, negative predictive value, accuracy and kappa statistics were calculated. A total of 299 frozen sections were obtained from 77 patients who underwent oral cancer resection, mean (3.88±0.76). Frozen sections' sensitivity in relation to permanent sections was 72.7% and specificity of 93.9%. The overall accuracy of the test was 90.9%. Kappa value was calculated to be 0.642, which showed a moderate agreement. Frozen sections are accurate enough to be used in assessing intraoperative margin assessment for tumour clearance.

Entities:  

Keywords:  Oral cavity, Squamous cell carcinoma, surgical treatment, intraoperative frozen section, accuracy.

Mesh:

Year:  2017        PMID: 28507379

Source DB:  PubMed          Journal:  J Pak Med Assoc        ISSN: 0030-9982            Impact factor:   0.781


  6 in total

1.  Intra-operative point-of-procedure delineation of oral cancer margins using optical coherence tomography.

Authors:  Sumsum P Sunny; Sagar Agarwal; Bonney Lee James; Emon Heidari; Anjana Muralidharan; Vishal Yadav; Vijay Pillai; Vivek Shetty; Zhongping Chen; Naveen Hedne; Petra Wilder-Smith; Amritha Suresh; Moni Abraham Kuriakose
Journal:  Oral Oncol       Date:  2019-03-15       Impact factor: 5.337

2.  Evaluation of the Sensitivity of Metabolic Profiling by Rapid Evaporative Ionization Mass Spectrometry: Toward More Radical Oral Cavity Cancer Resections.

Authors:  Pierre-Maxence Vaysse; Imke Demers; Mari F C M van den Hout; Wouter van de Worp; Ian G M Anthony; Laura W J Baijens; Bing I Tan; Martin Lacko; Lauretta A A Vaassen; Auke van Mierlo; Ramon C J Langen; Ernst-Jan M Speel; Ron M A Heeren; Tiffany Porta Siegel; Bernd Kremer
Journal:  Anal Chem       Date:  2022-05-03       Impact factor: 8.008

3.  Toluidine blue versus frozen section for assessment of mucosal tumor margins in oral squamous cell carcinoma.

Authors:  Hana'a Hezam Algadi; Amany Abd-Elhameed Abou-Bakr; Omer Mohammed Jamali; Louloua Mohamed Fathy
Journal:  BMC Cancer       Date:  2020-11-25       Impact factor: 4.430

Review 4.  Performance of Intraoperative Assessment of Resection Margins in Oral Cancer Surgery: A Review of Literature.

Authors:  Elisa M Barroso; Yassine Aaboubout; Lisette C van der Sar; Hetty Mast; Aniel Sewnaik; Jose A Hardillo; Ivo Ten Hove; Maria R Nunes Soares; Lars Ottevanger; Tom C Bakker Schut; Gerwin J Puppels; Senada Koljenović
Journal:  Front Oncol       Date:  2021-03-30       Impact factor: 6.244

Review 5.  Nanotechnology: a promising method for oral cancer detection and diagnosis.

Authors:  Xiao-Jie Chen; Xue-Qiong Zhang; Qi Liu; Jing Zhang; Gang Zhou
Journal:  J Nanobiotechnology       Date:  2018-06-11       Impact factor: 10.435

Review 6.  Specimen-driven intraoperative assessment of resection margins should be standard of care for oral cancer patients.

Authors:  Yassine Aaboubout; Ivo Ten Hove; Roeland W H Smits; Jose A Hardillo; Gerwin J Puppels; Senada Koljenovic
Journal:  Oral Dis       Date:  2020-09-13       Impact factor: 3.511

  6 in total

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