Literature DB >> 28502724

Durable Response to Afatinib in Lung Adenocarcinoma Harboring NRG1 Gene Fusions.

Nathan D Gay1, Ying Wang2, Carol Beadling2, Andrea Warrick2, Tanaya Neff2, Christopher L Corless2, Khaled Tolba3.   

Abstract

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Year:  2017        PMID： 28502724     DOI： 10.1016/j.jtho.2017.04.025

Source DB:  PubMed          Journal:  J Thorac Oncol        ISSN： 1556-0864            Impact factor:   15.609


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  17 in total

1.  High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden.

Authors:  Ryma Benayed; Michael Offin; Kerry Mullaney; Purvil Sukhadia; Kelly Rios; Patrice Desmeules; Ryan Ptashkin; Helen Won; Jason Chang; Darragh Halpenny; Alison M Schram; Charles M Rudin; David M Hyman; Maria E Arcila; Michael F Berger; Ahmet Zehir; Mark G Kris; Alexander Drilon; Marc Ladanyi
Journal:  Clin Cancer Res       Date:  2019-04-26       Impact factor: 12.531

2.  Neuregulin 1 (NRG1) fusion-positive high-grade spindle cell sarcoma: A distinct group of soft tissue tumors with metastatic potential.

Authors:  Josephine K Dermawan; Youran Zou; Cristina R Antonescu
Journal:  Genes Chromosomes Cancer       Date:  2021-11-30       Impact factor: 5.006

Review 3.  New Targets in Lung Cancer (Excluding EGFR, ALK, ROS1).

Authors:  Alessandro Russo; Ana Rita Lopes; Michael G McCusker; Sandra Gimenez Garrigues; Giuseppina R Ricciardi; Katherine E Arensmeyer; Katherine A Scilla; Ranee Mehra; Christian Rolfo
Journal:  Curr Oncol Rep       Date:  2020-04-16       Impact factor: 5.075

4.  Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers.

Authors:  Alexander Drilon; Romel Somwar; Biju P Mangatt; Henrik Edgren; Patrice Desmeules; Anja Ruusulehto; Roger S Smith; Lukas Delasos; Morana Vojnic; Andrew J Plodkowski; Joshua Sabari; Kenneth Ng; Joseph Montecalvo; Jason Chang; Huichun Tai; William W Lockwood; Victor Martinez; Gregory J Riely; Charles M Rudin; Mark G Kris; Maria E Arcila; Christopher Matheny; Ryma Benayed; Natasha Rekhtman; Marc Ladanyi; Gopinath Ganji
Journal:  Cancer Discov       Date:  2018-04-02       Impact factor: 39.397

5.  Novel Preclinical Patient-Derived Lung Cancer Models Reveal Inhibition of HER3 and MTOR Signaling as Therapeutic Strategies for NRG1 Fusion-Positive Cancers.

Authors:  Igor Odintsov; Marissa S Mattar; Allan J W Lui; Michael Offin; Christopher Kurzatkowski; Lukas Delasos; Inna Khodos; Marina Asher; Robert M Daly; Natasha Rekhtman; Elisa de Stanchina; Gopinath Ganji; Marc Ladanyi; Romel Somwar
Journal:  J Thorac Oncol       Date:  2021-04-08       Impact factor: 20.121

6.  Therapeutic Potential of Afatinib in NRG1 Fusion-Driven Solid Tumors: A Case Series.

Authors:  Jacques Cadranel; Stephen V Liu; Michaël Duruisseaux; Eva Branden; Yasushi Goto; Benjamin A Weinberg; Christoph Heining; Richard F Schlenk; Parneet Cheema; Martin R Jones; Alexander Drilon; Domenico Trombetta; Lucia Anna Muscarella; Khaled Tolba; Valerie Gounant; Agnieszka Cseh; Flavio Solca; Janessa J Laskin; Daniel J Renouf
Journal:  Oncologist       Date:  2020-09-23

7.  Identification of Targetable Gene Fusions and Structural Rearrangements to Foster Precision Medicine in KRAS Wild-Type Pancreatic Cancer.

Authors:  Michael J Fusco; Daryoush Saeed-Vafa; Estrella M Carballido; Theresa A Boyle; Mokenge Malafa; Kirsten L Blue; Jamie K Teer; Christine M Walko; Howard L McLeod; J Kevin Hicks; Martine Extermann; Jason B Fleming; Todd C Knepper; Dae Won Kim
Journal:  JCO Precis Oncol       Date:  2021-01-11

8.  NRG1 Genetic Variant Influences the Efficacy of Androgen-Deprivation Therapy in Men with Prostate Cancer.

Authors:  Shu-Pin Huang; Yei-Tsung Chen; Lih-Chyang Chen; Cheng-Hsueh Lee; Chao-Yuan Huang; Chia-Cheng Yu; Victor C Lin; Te-Ling Lu; Bo-Ying Bao
Journal:  Biomedicines       Date:  2021-05-10

9.  Clinical Relevance of PD-L1 Expression and CD8+ T Cells' Infiltration in Patients With Lung Invasive Mucinous Adenocarcinoma.

Authors:  Xiaoling Xu; Na Li; Ding Wang; Wei Chen; Yun Fan
Journal:  Front Oncol       Date:  2021-06-24       Impact factor: 6.244

10.  Clinicopathologic Features and Response to Therapy of NRG1 Fusion-Driven Lung Cancers: The eNRGy1 Global Multicenter Registry.

Authors:  Alexander Drilon; Michael Duruisseaux; Ji-Youn Han; Masaoki Ito; Christina Falcon; Soo-Ryum Yang; Yonina R Murciano-Goroff; Haiquan Chen; Morihito Okada; Miguel Angel Molina; Marie Wislez; Philippe Brun; Clarisse Dupont; Eva Branden; Giulio Rossi; Alexa Schrock; Siraj Ali; Valérie Gounant; Fanny Magne; Torsten Gerriet Blum; Alison M Schram; Isabelle Monnet; Jin-Yuan Shih; Joshua Sabari; Maurice Pérol; Viola W Zhu; Misako Nagasaka; Robert Doebele; D Ross Camidge; Maria Arcila; Sai-Hong Ignatius Ou; Denis Moro-Sibilot; Rafael Rosell; Lucia Anna Muscarella; Stephen V Liu; Jacques Cadranel
Journal:  J Clin Oncol       Date:  2021-06-02       Impact factor: 50.717
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