| Literature DB >> 28501077 |
Jia Li1, Changlong An1, Lei Kang1, William E Mitch1, Yanlin Wang2.
Abstract
CKD is a global public health problem. Renal fibrosis is a final common pathway leading to progressive loss of function in CKD. The degree of renal fibrosis predicts the prognosis of CKD. Recent studies have shown that bone marrow-derived fibroblasts contribute significantly to the development of renal fibrosis, which may yield novel therapeutic strategy for fibrotic kidney disease. Therefore, it is imperative to accurately assess the degree of renal fibrosis noninvasively to identify those patients who can benefit from antifibrotic therapy. In this review, we summarize recent advances in the assessment of renal fibrosis by magnetic resonance imaging. Published by Elsevier Inc.Entities:
Keywords: Chronic kidney disease; Extracellular matrix; Fibroblast; Fibrosis; Magnetic resonance imaging
Mesh:
Year: 2017 PMID: 28501077 PMCID: PMC5433256 DOI: 10.1053/j.ackd.2017.03.005
Source DB: PubMed Journal: Adv Chronic Kidney Dis ISSN: 1548-5595 Impact factor: 3.620