BACKGROUND AND OBJECTIVE: To compare macular vessel density (VD) and foveal avascular zone (FAZ) area in healthy individuals using two different optical coherence tomography angiography (OCTA) devices. PATIENTS AND METHODS: In this prospective, comparative study, 25 eyes of 14 healthy subjects underwent fovea-centered 3 mm × 3 mm OCTA-imaging using the Triton (Topcon, Tokyo, Japan) and RS-3000 (Nidek, Gamagori, Japan) OCTA devices. Superficial and deep retinal layers (SRL/DRL) and FAZ were manually graded after threshold standardization to determine macular VD and area of the FAZ. RESULTS: The mean difference in the VD between the two devices was 0.105 and 0.096, and the coefficient of variation (CV) was 19.59% and 16.90% for the SRL and DRL, respectively. After skeletonization of vessels to remove variation related to vessel width, the mean difference was 0.174 mm-1 and 0.516 mm-1, and the CV was 3.49% and 1.07% for SRL and DRL, respectively. The mean difference of FAZ area was 0.001 mm2 and 0.010 mm2 in the SRL and DRL, respectively, and the CV was 2.17% and 5.74% for the SRL and DRL, respectively. CONCLUSION: Macular VD using skeletonized mapping and FAZ area in SRL and DRL were statistically similar between the two devices, demonstrating a possible comparison of quantitative values between different OCTA devices. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:385-391.]. Copyright 2017, SLACK Incorporated.
BACKGROUND AND OBJECTIVE: To compare macular vessel density (VD) and foveal avascular zone (FAZ) area in healthy individuals using two different optical coherence tomography angiography (OCTA) devices. PATIENTS AND METHODS: In this prospective, comparative study, 25 eyes of 14 healthy subjects underwent fovea-centered 3 mm × 3 mm OCTA-imaging using the Triton (Topcon, Tokyo, Japan) and RS-3000 (Nidek, Gamagori, Japan) OCTA devices. Superficial and deep retinal layers (SRL/DRL) and FAZ were manually graded after threshold standardization to determine macular VD and area of the FAZ. RESULTS: The mean difference in the VD between the two devices was 0.105 and 0.096, and the coefficient of variation (CV) was 19.59% and 16.90% for the SRL and DRL, respectively. After skeletonization of vessels to remove variation related to vessel width, the mean difference was 0.174 mm-1 and 0.516 mm-1, and the CV was 3.49% and 1.07% for SRL and DRL, respectively. The mean difference of FAZ area was 0.001 mm2 and 0.010 mm2 in the SRL and DRL, respectively, and the CV was 2.17% and 5.74% for the SRL and DRL, respectively. CONCLUSION: Macular VD using skeletonized mapping and FAZ area in SRL and DRL were statistically similar between the two devices, demonstrating a possible comparison of quantitative values between different OCTA devices. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:385-391.]. Copyright 2017, SLACK Incorporated.
Authors: Henrik Faatz; Kai Rothaus; Martin Ziegler; Marius Book; Claudia Lommatzsch; Georg Spital; Matthias Gutfleisch; Daniel Pauleikhoff; Albrecht Lommatzsch Journal: Clin Ophthalmol Date: 2020-10-09
Authors: Itika Garg; Chibuike Uwakwe; Rongrong Le; Edward S Lu; Ying Cui; Karen M Wai; Raviv Katz; Ying Zhu; Jade Y Moon; Chloe Y Li; Inês Laíns; Dean Eliott; Tobias Elze; Leo A Kim; David M Wu; Joan W Miller; Deeba Husain; Demetrios G Vavvas; John B Miller Journal: Ophthalmol Sci Date: 2022-03-18
Authors: Florence Coscas; Diogo Cabral; Telmo Pereira; Carlos Geraldes; Hemaxi Narotamo; Alexandra Miere; Marco Lupidi; Alexandre Sellam; Ana Papoila; Gabriel Coscas; Eric Souied Journal: PLoS One Date: 2018-10-09 Impact factor: 3.240
Authors: Henrik Faatz; Kai Rothaus; Martin Ziegler; Marius Book; Britta Heimes-Bussmann; Daniel Pauleikhoff; Albrecht Lommatzsch Journal: Biomedicines Date: 2022-03-17