Literature DB >> 28486828

Ruta chalepensis L. (Rutaceae) leaf extract: chemical composition, antioxidant and hypoglicaemic activities.

M R Loizzo1, T Falco1, M Bonesi1, V Sicari2, R Tundis1, M Bruno3.   

Abstract

Ruta chalepensis L. (Rutaceae) leaf extract was investigated for its chemical profile and antioxidant and hypoglycaemic properties. The antioxidant effects were investigated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), β-carotene bleaching, and metal chelating activity assays. The carbohydrate-hydrolysing enzymes inhibition assay was used to test the hypoglycaemic potential. R. chalepensis showed a high content of hesperidin and rutin with values of 591.9 and 266.7 mg/g dry extract, respectively. The extract exhibited a promising protection of lipid peroxidation (IC50 value of 16.9 μg/mL) and inhibited both α-amylase and α-glucosidase enzymes in a concentration-dependent manner. The highest activity was found against α-amylase (IC50 value of 69.0 μg/mL). The obtained results support the use of R. chalepensis leaves as healthy food ingredients.

Entities:  

Keywords:  HPLC analysis; Ruta chalepensis; antioxidant activity; hypoglycaemic activity; leaves

Mesh：

Substances：

Year:  2017        PMID： 28486828     DOI： 10.1080/14786419.2017.1326491

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  6 in total

1.  Callus-Mediated High-Frequency Plant Regeneration, Phytochemical Profiling, Antioxidant Activity and Genetic Stability in Ruta chalepensis L.

Authors:  Ahmed A Qahtan; Mohammad Faisal; Abdulrahman A Alatar; Eslam M Abdel-Salam
Journal:  Plants (Basel)       Date:  2022-06-20

Review 2.  Evaluating the In Vitro Potential of Natural Extracts to Protect Lipids from Oxidative Damage.

Authors:  Rafael Félix; Patrícia Valentão; Paula B Andrade; Carina Félix; Sara C Novais; Marco F L Lemos
Journal:  Antioxidants (Basel)       Date:  2020-03-11

Review 3.  Hesperidin: A Therapeutic Agent For Obesity.

Authors:  Haijun Xiong; Jin Wang; Qian Ran; Guanhua Lou; Chengyi Peng; Qingxia Gan; Ju Hu; Jilin Sun; Renchuan Yao; Qinwan Huang
Journal:  Drug Des Devel Ther       Date:  2019-11-12       Impact factor: 4.162

4.  Phenolic Characterization Using cLC-DAD Analysis and Evaluation of In Vitro and In Vivo Pharmacological Activities of Ruta tuberculata Forssk.

Authors:  Asma Saidi; Leila Hambaba; Mohamed Sabri Bensaad; Mohamed Akram Melakhessou; Chawki Bensouici; Nouicer Ferhat; Mohamed Amine Kahoul; Mahmoud Helal; Rokayya Sami; Saif A Alharthy; Roua S Baty; Nouf H Alsubhi; Ghadeer I Alrefaei; Abeer Elhakem; Sarah Alharthi; Fahmy G Elsaid; Ali A Shati
Journal:  Antioxidants (Basel)       Date:  2022-07-11

5.  Phytochemical Characterization, and Antioxidant and Antimicrobial Properties of Agitated Cultures of Three Rue Species: Ruta chalepensis, Ruta corsica, and Ruta graveolens.

Authors:  Agnieszka Szewczyk; Andreana Marino; Jessica Molinari; Halina Ekiert; Natalizia Miceli
Journal:  Antioxidants (Basel)       Date:  2022-03-20

6.  Phytochemical Screening and in-vitro Evaluation of Antibacterial Activities of Echinops amplexicaulis, Ruta chalepensis and Salix subserrata Against Selected Pathogenic Bacterial Strains in West Shewa Zone, Ethiopia.

Authors:  Lencho Megersa Marami; Getachew Mulatu Dilba; Dagmawit Atalel Babele; Edilu Jorga Sarba; Askale Gizaw; Wakuma Mitiku Bune; Morka Dandecha Bayu; Petros Admasu; Abraham Mekbeb; Miressa Tadesse; Kebede Abdisa; Dejene Bayisa
Journal:  J Exp Pharmacol       Date:  2021-05-18
  6 in total

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