Literature DB >> 28486121

Mitochondrial Homeostasis: How Do Dimers of Mitofusins Mediate Mitochondrial Fusion?

Oliver Daumke1, Aurélien Roux2.   

Abstract

Mitochondria have high fusion and fission rates to maintain their size and number throughout the cell cycle. How is fusion mediated? New structural studies propose mechanisms by which the dynamin-like mitofusin proteins promote fusion of mitochondria.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID: 28486121     DOI: 10.1016/j.cub.2017.03.024

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  20 in total

1.  A catalytic domain variant of mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion.

Authors:  Emily A Engelhart; Suzanne Hoppins
Journal:  J Biol Chem       Date:  2019-04-01       Impact factor: 5.157

Review 2.  Mitochondrial Proteolysis and Metabolic Control.

Authors:  Sofia Ahola; Thomas Langer; Thomas MacVicar
Journal:  Cold Spring Harb Perspect Biol       Date:  2019-07-01       Impact factor: 10.005

3.  Finding a new balance to cure Charcot-Marie-Tooth 2A.

Authors:  Keiko Iwata; Luca Scorrano
Journal:  J Clin Invest       Date:  2019-03-18       Impact factor: 14.808

Review 4.  Mitochondrial dynamics: The dynamin superfamily and execution by collusion.

Authors:  Rajesh Ramachandran
Journal:  Semin Cell Dev Biol       Date:  2017-07-25       Impact factor: 7.727

5.  Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase.

Authors:  Kyle P Smith; Pamela J Focia; Srinivas Chakravarthy; Eric C Landahl; Julian L Klosowiak; Sarah E Rice; Douglas M Freymann
Journal:  J Struct Biol       Date:  2020-10-24       Impact factor: 2.867

6.  Mitofusin gain and loss of function drive pathogenesis in Drosophila models of CMT2A neuropathy.

Authors:  Najla El Fissi; Manuel Rojo; Aїcha Aouane; Esra Karatas; Gabriela Poliacikova; Claudine David; Julien Royet; Thomas Rival
Journal:  EMBO Rep       Date:  2018-06-13       Impact factor: 8.807

Review 7.  Mitofusin 2: from functions to disease.

Authors:  Riccardo Filadi; Diana Pendin; Paola Pizzo
Journal:  Cell Death Dis       Date:  2018-02-28       Impact factor: 8.469

8.  The GDP-Bound State of Mitochondrial Mfn1 Induces Membrane Adhesion of Apposing Lipid Vesicles through a Cooperative Binding Mechanism.

Authors:  Andrés Tolosa-Díaz; Víctor G Almendro-Vedia; Paolo Natale; Iván López-Montero
Journal:  Biomolecules       Date:  2020-07-21

9.  Structural basis for membrane tethering by a bacterial dynamin-like pair.

Authors:  Jiwei Liu; Jeffrey K Noel; Harry H Low
Journal:  Nat Commun       Date:  2018-08-21       Impact factor: 14.919

Review 10.  Mitochondrial function in development and disease.

Authors:  Marlies P Rossmann; Sonia M Dubois; Suneet Agarwal; Leonard I Zon
Journal:  Dis Model Mech       Date:  2021-06-11       Impact factor: 5.758

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