Literature DB >> 28480751

CT Pulmonary Angiography in Young Women.

Paul D Stein1, Fadi Matta1, Kate E Hughes1, Mary J Hughes1.   

Abstract

The purpose was to determine whether young women in the emergency department who received computed tomographic (CT) pulmonary angiograms were evaluated to receive lower dose imaging or no imaging, recognizing that the risks of radiation are particularly high in young women. This was a retrospective cohort investigation of women aged 18 to 29 years seen for suspected acute pulmonary embolism in emergency departments of 5 regional hospitals from May 1, 2015 to April 30, 2016. Computed tomographic (CT) pulmonary angiograms were obtained in 379 young women. Pulmonary embolism was diagnosed by CT angiography in 2.1%. A Wells probability score could be calculated in 11.9%. D-dimer was obtained in 46.2% and a chest radiograph was obtained in 41.7%. Among patients with a normal chest radiograph, 3.9% had a lung scan. Venous ultrasound of the lower extremities was obtained in 1.8%. Each had an elevated D-dimer. Among the young women who received CT angiograms, 53 were pregnant. In 17.0% of pregnant women, a Wells clinical probability score could be calculated from the medical record. D-dimer in pregnant women was obtained in 30.2%, chest radiograph in 22.6%, lung scan in 11.3%, and venous ultrasound of the lower extremities in none. In conclusion, young women and pregnant women often received CT pulmonary angiograms for suspected acute pulmonary embolism without an objective clinical assessment, measurement of D-dimer, lung scintiscan, or venous ultrasound, which may have eliminated the need for CT pulmonary angiography in many instances.

Entities:  

Keywords:  CT angiography; pregnancy; pulmonary embolism; radiation; women

Mesh:

Substances:

Year:  2017        PMID: 28480751      PMCID: PMC6714652          DOI: 10.1177/1076029617707038

Source DB:  PubMed          Journal:  Clin Appl Thromb Hemost        ISSN: 1076-0296            Impact factor:   2.389


  23 in total

1.  British Thoracic Society guidelines for the management of suspected acute pulmonary embolism.

Authors: 
Journal:  Thorax       Date:  2003-06       Impact factor: 9.139

Review 2.  Management of suspected acute pulmonary embolism in the era of CT angiography: a statement from the Fleischner Society.

Authors:  Martine Remy-Jardin; Massimo Pistolesi; Lawrence R Goodman; Warren B Gefter; Alexander Gottschalk; John R Mayo; H Dirk Sostman
Journal:  Radiology       Date:  2007-09-11       Impact factor: 11.105

3.  Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer.

Authors:  P S Wells; D R Anderson; M Rodger; J S Ginsberg; C Kearon; M Gent; A G Turpie; J Bormanis; J Weitz; M Chamberlain; D Bowie; D Barnes; J Hirsh
Journal:  Thromb Haemost       Date:  2000-03       Impact factor: 5.249

4.  Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II investigators.

Authors:  Paul D Stein; Pamela K Woodard; John G Weg; Thomas W Wakefield; Victor F Tapson; H Dirk Sostman; Thomas A Sos; Deborah A Quinn; Kenneth V Leeper; Russell D Hull; Charles A Hales; Alexander Gottschalk; Lawrence R Goodman; Sarah E Fowler; John D Buckley
Journal:  Am J Med       Date:  2006-12       Impact factor: 4.965

5.  Radiation dose to patients from radiopharmaceuticals (addendum 2 to ICRP publication 53).

Authors: 
Journal:  Ann ICRP       Date:  1998

6.  Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography.

Authors:  Arne van Belle; Harry R Büller; Menno V Huisman; Peter M Huisman; Karin Kaasjager; Pieter W Kamphuisen; Mark H H Kramer; Marieke J H A Kruip; Johanna M Kwakkel-van Erp; Frank W G Leebeek; Mathilde Nijkeuter; Martin H Prins; Maaike Sohne; Lidwine W Tick
Journal:  JAMA       Date:  2006-01-11       Impact factor: 56.272

Review 7.  D-dimer testing in pregnancy.

Authors:  Sabine Eichinger
Journal:  Pathophysiol Haemost Thromb       Date:  2003 Sep-2004 Dec

8.  Overview of Prospective Investigation of Pulmonary Embolism Diagnosis II.

Authors:  Alexander Gottschalk; Paul D Stein; Lawrence R Goodman; H Dirk Sostman
Journal:  Semin Nucl Med       Date:  2002-07       Impact factor: 4.446

9.  Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC).

Authors:  Adam Torbicki; Arnaud Perrier; Stavros Konstantinides; Giancarlo Agnelli; Nazzareno Galiè; Piotr Pruszczyk; Frank Bengel; Adrian J B Brady; Daniel Ferreira; Uwe Janssens; Walter Klepetko; Eckhard Mayer; Martine Remy-Jardin; Jean-Pierre Bassand
Journal:  Eur Heart J       Date:  2008-08-30       Impact factor: 29.983

10.  Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography.

Authors:  Andrew J Einstein; Milena J Henzlova; Sanjay Rajagopalan
Journal:  JAMA       Date:  2007-07-18       Impact factor: 56.272

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.