| Literature DB >> 28478793 |
Heather B Rigby1, Sara Rehan2, Barbara Hill-Taylor2, Kara Matheson3, Ingrid Sketris2.
Abstract
Several evidence-informed treatment guidelines recommend against the use of typical antipsychotics in patients with Parkinson's disease; of the atypical antipsychotics, clozapine and quetiapine are preferred. The purpose of this study is to determine the frequency with which potentially inappropriate antipsychotics are dispensed to older adults in Nova Scotia who are on levodopa-containing medications. In this cohort, 59.9% were dispensed a preferred atypical antipsychotic and 12.6% a potentially harmful typical antipsychotic. Our results suggest that potentially inappropriate prescribing practices are common in the neuropsychiatric management of patients with parkinsonism and that there is an opportunity for education and improvement in prescribing practices.Entities:
Keywords: Lewy bodies; Parkinson’s disease; antipsychotic agents; physician prescribing patterns
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Year: 2017 PMID: 28478793 DOI: 10.1017/cjn.2017.36
Source DB: PubMed Journal: Can J Neurol Sci ISSN: 0317-1671 Impact factor: 2.104