Literature DB >> 28478793

Antipsychotic Prescribing Practices in Those with Parkinsonism: Adherence to Guidelines.

Heather B Rigby1, Sara Rehan2, Barbara Hill-Taylor2, Kara Matheson3, Ingrid Sketris2.   

Abstract

Several evidence-informed treatment guidelines recommend against the use of typical antipsychotics in patients with Parkinson's disease; of the atypical antipsychotics, clozapine and quetiapine are preferred. The purpose of this study is to determine the frequency with which potentially inappropriate antipsychotics are dispensed to older adults in Nova Scotia who are on levodopa-containing medications. In this cohort, 59.9% were dispensed a preferred atypical antipsychotic and 12.6% a potentially harmful typical antipsychotic. Our results suggest that potentially inappropriate prescribing practices are common in the neuropsychiatric management of patients with parkinsonism and that there is an opportunity for education and improvement in prescribing practices.

Entities:  

Keywords:  Lewy bodies; Parkinson’s disease; antipsychotic agents; physician prescribing patterns

Mesh:

Substances:

Year:  2017        PMID: 28478793     DOI: 10.1017/cjn.2017.36

Source DB:  PubMed          Journal:  Can J Neurol Sci        ISSN: 0317-1671            Impact factor:   2.104


  4 in total

1.  Frequency of and risk factors for potentially inappropriate medication use in Parkinson's disease.

Authors:  Danielle S Abraham; Thanh Phuong Pham Nguyen; Sean Hennessy; Daniel Weintraub; Shelly L Gray; Dawei Xie; Allison W Willis
Journal:  Age Ageing       Date:  2020-08-24       Impact factor: 10.668

2.  Inappropriate use of clinical practices in Canada: a systematic review.

Authors:  Janet E Squires; Danielle Cho-Young; Laura D Aloisio; Robert Bell; Stephen Bornstein; Susan E Brien; Simon Decary; Melissa Demery Varin; Mark Dobrow; Carole A Estabrooks; Ian D Graham; Megan Greenough; Doris Grinspun; Michael Hillmer; Tanya Horsley; Jiale Hu; Alan Katz; Christina Krause; John Lavis; Wendy Levinson; Adrian Levy; Michelina Mancuso; Steve Morgan; Letitia Nadalin-Penno; Andrew Neuner; Tamara Rader; Wilmer J Santos; Gary Teare; Joshua Tepper; Amanda Vandyk; Michael Wilson; Jeremy M Grimshaw
Journal:  CMAJ       Date:  2022-02-28       Impact factor: 16.859

3.  Trends and Contributing Factors for Prescribing Antipsychotics in Newly Diagnosed Parkinson's Disease Patients: A Population-Based Study.

Authors:  Khalid Orayj
Journal:  Risk Manag Healthc Policy       Date:  2021-06-04

4.  Low continuation of antipsychotic therapy in Parkinson disease - intolerance, ineffectiveness, or inertia?

Authors:  Thanh Phuong Pham Nguyen; Danielle S Abraham; Dylan Thibault; Daniel Weintraub; Allison W Willis
Journal:  BMC Neurol       Date:  2021-06-24       Impact factor: 2.474

  4 in total

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