Literature DB >> 28475890

Metabolic Instruction of Immunity.

Michael D Buck1, Ryan T Sowell2, Susan M Kaech3, Erika L Pearce4.   

Abstract

Choices have consequences. Immune cells survey and migrate throughout the body and sometimes take residence in niche environments with distinct communities of cells, extracellular matrix, and nutrients that may differ from those in which they matured. Imbedded in immune cell physiology are metabolic pathways and metabolites that not only provide energy and substrates for growth and survival, but also instruct effector functions, differentiation, and gene expression. This review of immunometabolism will reference the most recent literature to cover the choices that environments impose on the metabolism and function of immune cells and highlight their consequences during homeostasis and disease.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  aerobic glycolysis; barrier immunity; checkpoint blockade; immunometabolism; immunotherapy; metabolism; mitochondria; mitochondrial dynamics; mucosa; tumor microenvironment

Mesh：

Year:  2017        PMID： 28475890      PMCID： PMC5648021          DOI： 10.1016/j.cell.2017.04.004

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  154 in total

1.  Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans.

Authors:  Saverio Cinti; Grant Mitchell; Giorgio Barbatelli; Incoronata Murano; Enzo Ceresi; Emanuela Faloia; Shupei Wang; Melanie Fortier; Andrew S Greenberg; Martin S Obin
Journal:  J Lipid Res       Date:  2005-09-08       Impact factor: 5.922

2.  Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells.

Authors:  Yukihiro Furusawa; Yuuki Obata; Shinji Fukuda; Takaho A Endo; Gaku Nakato; Daisuke Takahashi; Yumiko Nakanishi; Chikako Uetake; Keiko Kato; Tamotsu Kato; Masumi Takahashi; Noriko N Fukuda; Shinnosuke Murakami; Eiji Miyauchi; Shingo Hino; Koji Atarashi; Satoshi Onawa; Yumiko Fujimura; Trevor Lockett; Julie M Clarke; David L Topping; Masaru Tomita; Shohei Hori; Osamu Ohara; Tatsuya Morita; Haruhiko Koseki; Jun Kikuchi; Kenya Honda; Koji Hase; Hiroshi Ohno
Journal:  Nature       Date:  2013-11-13       Impact factor: 49.962

3.  Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis.

Authors:  Mathias Wenes; Min Shang; Mario Di Matteo; Jermaine Goveia; Rosa Martín-Pérez; Jens Serneels; Hans Prenen; Bart Ghesquière; Peter Carmeliet; Massimiliano Mazzone
Journal:  Cell Metab       Date:  2016-10-20       Impact factor: 27.287

4.  The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

Authors:  Ruoning Wang; Christopher P Dillon; Lewis Zhichang Shi; Sandra Milasta; Robert Carter; David Finkelstein; Laura L McCormick; Patrick Fitzgerald; Hongbo Chi; Joshua Munger; Douglas R Green
Journal:  Immunity       Date:  2011-12-23       Impact factor: 31.745

5.  Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells.

Authors:  Heather Kopf; Gonzalo M de la Rosa; O M Zack Howard; Xin Chen
Journal:  Int Immunopharmacol       Date:  2007-09-20       Impact factor: 4.932

6.  Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase.

Authors:  David H Munn; Madhav D Sharma; Jeffrey R Lee; Kanchan G Jhaver; Theodore S Johnson; Derin B Keskin; Brendan Marshall; Phillip Chandler; Scott J Antonia; Russell Burgess; Craig L Slingluff; Andrew L Mellor
Journal:  Science       Date:  2002-09-13       Impact factor: 47.728

7.  De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

Authors:  Luciana Berod; Christin Friedrich; Amrita Nandan; Jenny Freitag; Stefanie Hagemann; Kirsten Harmrolfs; Aline Sandouk; Christina Hesse; Carla N Castro; Heike Bähre; Sarah K Tschirner; Nataliya Gorinski; Melanie Gohmert; Christian T Mayer; Jochen Huehn; Evgeni Ponimaskin; Wolf-Rainer Abraham; Rolf Müller; Matthias Lochner; Tim Sparwasser
Journal:  Nat Med       Date:  2014-10-05       Impact factor: 53.440

8.  Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function.

Authors:  Maria L Balmer; Eric H Ma; Glenn R Bantug; Jasmin Grählert; Simona Pfister; Timo Glatter; Annaïse Jauch; Sarah Dimeloe; Emma Slack; Philippe Dehio; Magdalena A Krzyzaniak; Carolyn G King; Anne-Valérie Burgener; Marco Fischer; Leyla Develioglu; Réka Belle; Mike Recher; Weldy V Bonilla; Andrew J Macpherson; Siegfried Hapfelmeier; Russell G Jones; Christoph Hess
Journal:  Immunity       Date:  2016-05-17       Impact factor: 31.745

9.  Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton.

Authors:  Hai Hu; Ashish Juvekar; Costas A Lyssiotis; Evan C Lien; John G Albeck; Doogie Oh; Gopal Varma; Yin Pun Hung; Soumya Ullas; Josh Lauring; Pankaj Seth; Mark R Lundquist; Dean R Tolan; Aaron K Grant; Daniel J Needleman; John M Asara; Lewis C Cantley; Gerburg M Wulf
Journal:  Cell       Date:  2016-01-28       Impact factor: 41.582

10.  PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.

Authors:  David K Finlay; Ella Rosenzweig; Linda V Sinclair; Carmen Feijoo-Carnero; Jens L Hukelmann; Julia Rolf; Andrey A Panteleyev; Klaus Okkenhaug; Doreen A Cantrell
Journal:  J Exp Med       Date:  2012-11-26       Impact factor: 14.307
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  363 in total

1.  Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling.

Authors:  Xingguang Liu; Peng Zhang; Yunkai Zhang; Zheng Wang; Sheng Xu; Yingke Li; Wanwan Huai; Qingqing Zhou; Xiang Chen; Xi Chen; Nan Li; Peng Wang; Yunsen Li; Xuetao Cao
Journal:  Cell Res       Date:  2018-12-04       Impact factor: 25.617

2.  Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease.

Authors:  Chetan V Jawale; Kritika Ramani; De-Dong Li; Bianca M Coleman; Rohan S Oberoi; Saran Kupul; Li Lin; Jigar V Desai; Greg M Delgoffe; Michail S Lionakis; Filitsa H Bender; Alexander J Prokopienko; Thomas D Nolin; Sarah L Gaffen; Partha S Biswas
Journal:  Sci Transl Med       Date:  2020-06-17       Impact factor: 17.956

Review 3.  Applications of metabolomics to study cancer metabolism.

Authors:  Akash K Kaushik; Ralph J DeBerardinis
Journal:  Biochim Biophys Acta Rev Cancer       Date:  2018-04-25       Impact factor: 10.680

4.  Self-Regulation of Memory CD8 T Cell Metabolism through Extracellular ATP Signaling.

Authors:  Kelsey M Wanhainen; Stephen C Jameson; Henrique Borges da Silva
Journal:  Immunometabolism       Date:  2019-07-23

Review 5.  Metabolic Regulation of Cell Fate and Function.

Authors:  Shohini Ghosh-Choudhary; Jie Liu; Toren Finkel
Journal:  Trends Cell Biol       Date:  2020-01-23       Impact factor: 20.808

6.  T Cell-Expressed microRNA-155 Reduces Lifespan in a Mouse Model of Age-Related Chronic Inflammation.

Authors:  H Atakan Ekiz; Andrew G Ramstead; Soh-Hyun Lee; Morgan C Nelson; Kaylyn M Bauer; Jared A Wallace; Ruozhen Hu; June L Round; Jared Rutter; Micah J Drummond; Dinesh S Rao; Ryan M O'Connell
Journal:  J Immunol       Date:  2020-03-11       Impact factor: 5.422

Review 7.  Helper T cell differentiation.

Authors:  Jordy Saravia; Nicole M Chapman; Hongbo Chi
Journal:  Cell Mol Immunol       Date:  2019-03-12       Impact factor: 11.530

8.  Translating immunometabolism: towards curing human diseases by targeting metabolic processes underpinning the immune response.

Authors:  S Dimeloe; C Mauro
Journal:  Clin Exp Immunol       Date:  2019-08       Impact factor: 4.330

Review 9.  Metabolic reprogramming and apoptosis sensitivity: Defining the contours of a T cell response.

Authors:  Kelsey Voss; Sasha E Larsen; Andrew L Snow
Journal:  Cancer Lett       Date:  2017-09-01       Impact factor: 8.679

10.  Ruthenium pyridyl thiocyanate complex increased the production of pro-inflammatory TNFα and IL1β cytokines by the LPS stimulated mammalian macrophages in vitro.

Authors:  Furkan Ayaz
Journal:  Mol Biol Rep       Date:  2018-10-04       Impact factor: 2.316
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