Ki Hyuk Sung1, Chin Youb Chung1, Kyoung Min Lee1, Byung Chae Cho2, Seung Jun Moon1, Jaeyoung Kim3, Moon Seok Park4. 1. Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Sungnam, Korea. 2. Department of Orthopaedic Surgery, Seoul Jaeil Hospital, Jisan-dong, Pyeongtack, Korea. 3. Department of Orthopaedic Surgery, H Plus Yangji Hospital, Seoul, Korea. 4. Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Sungnam, Korea. Electronic address: pmsmed@gmail.com.
Abstract
OBJECTIVE: To assess differences in body composition according to gross motor function in children with cerebral palsy (CP) compared with healthy controls. DESIGN: Retrospective case-control study. SETTING: Tertiary referral center for CP. PARTICIPANTS: Participants (N=146) comprised consecutive patients with CP (n=100; mean age, 11.5±4.2y) who were admitted for orthopedic surgery between May 2014 and March 2016 and typically developing children (TDC, n=46; control group). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Bioelectrical impedance analysis (BIA) was used to assess body composition, including body fat, soft lean mass (SLM), fat-free mass (FFM), skeletal muscle mass (SMM), body cell mass (BCM), bone mineral content (BMC), and basal metabolic rate. Body composition measures were compared according to Gross Motor Function Classification System (GMFCS) level, as well as between children with CP and TDC. RESULTS: Children with CP with GMFCS levels IV and V had a lower height, weight, and body mass index than those with GMFCS levels I to III. Children with CP with GMFCS levels IV and V had a significantly lower SLM, SLM index, FFM, FFM index, SMM, SMM index, BCM, BCM index, BMC, and BMC index than those with GMFCS levels I to III and TDC. GMFCS level significantly affected SLM and BMC. CONCLUSIONS: Body composition analysis using BIA showed that nonambulatory children with CP had significantly lower FFM, SLM, SMM, BCM, and BMC than ambulatory children with CP and TDC. However, further study is required to allow the use of BIA as a valid nutritional assessment tool in patients with CP.
OBJECTIVE: To assess differences in body composition according to gross motor function in children with cerebral palsy (CP) compared with healthy controls. DESIGN: Retrospective case-control study. SETTING: Tertiary referral center for CP. PARTICIPANTS: Participants (N=146) comprised consecutive patients with CP (n=100; mean age, 11.5±4.2y) who were admitted for orthopedic surgery between May 2014 and March 2016 and typically developing children (TDC, n=46; control group). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Bioelectrical impedance analysis (BIA) was used to assess body composition, including body fat, soft lean mass (SLM), fat-free mass (FFM), skeletal muscle mass (SMM), body cell mass (BCM), bone mineral content (BMC), and basal metabolic rate. Body composition measures were compared according to Gross Motor Function Classification System (GMFCS) level, as well as between children with CP and TDC. RESULTS:Children with CP with GMFCS levels IV and V had a lower height, weight, and body mass index than those with GMFCS levels I to III. Children with CP with GMFCS levels IV and V had a significantly lower SLM, SLM index, FFM, FFM index, SMM, SMM index, BCM, BCM index, BMC, and BMC index than those with GMFCS levels I to III and TDC. GMFCS level significantly affected SLM and BMC. CONCLUSIONS: Body composition analysis using BIA showed that nonambulatory children with CP had significantly lower FFM, SLM, SMM, BCM, and BMC than ambulatory children with CP and TDC. However, further study is required to allow the use of BIA as a valid nutritional assessment tool in patients with CP.
Authors: Kathleen J Motil; Suzanne Geerts; Fran Annese; Jeffrey L Neul; Tim Benke; Eric Marsh; David Lieberman; Steven A Skinner; Daniel G Glaze; Peter Heydemann; Arthur Beisang; Shannon Standridge; Robin Ryther; Jane B Lane; Lloyd Edwards; Alan K Percy Journal: J Pediatr Date: 2022-01-19 Impact factor: 6.314