Literature DB >> 28462817

Excision of Latent HIV-1 from Infected Cells In Vivo: An Important Step Forward.

Harshana S De Silva Feelixge1, Keith R Jerome2.   

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Year:  2017        PMID： 28462817      PMCID： PMC5417841          DOI： 10.1016/j.ymthe.2017.04.009

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  14 in total

1.  Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy.

Authors:  D Finzi; J Blankson; J D Siliciano; J B Margolick; K Chadwick; T Pierson; K Smith; J Lisziewicz; F Lori; C Flexner; T C Quinn; R E Chaisson; E Rosenberg; B Walker; S Gange; J Gallant; R F Siliciano
Journal:  Nat Med       Date:  1999-05       Impact factor: 53.440

2.  Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

Authors:  Janet D Siliciano; Joleen Kajdas; Diana Finzi; Thomas C Quinn; Karen Chadwick; Joseph B Margolick; Colin Kovacs; Stephen J Gange; Robert F Siliciano
Journal:  Nat Med       Date:  2003-05-18       Impact factor: 53.440

Review 3.  Genome editing and the next generation of antiviral therapy.

Authors:  Daniel Stone; Nixon Niyonzima; Keith R Jerome
Journal:  Hum Genet       Date:  2016-06-08       Impact factor: 4.132

4.  A Combinatorial CRISPR-Cas9 Attack on HIV-1 DNA Extinguishes All Infectious Provirus in Infected T Cell Cultures.

Authors:  Gang Wang; Na Zhao; Ben Berkhout; Atze T Das
Journal:  Cell Rep       Date:  2016-12-13       Impact factor: 9.423

5.  In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models.

Authors:  Chaoran Yin; Ting Zhang; Xiying Qu; Yonggang Zhang; Raj Putatunda; Xiao Xiao; Fang Li; Weidong Xiao; Huaqing Zhao; Shen Dai; Xuebin Qin; Xianming Mo; Won-Bin Young; Kamel Khalili; Wenhui Hu
Journal:  Mol Ther       Date:  2017-03-30       Impact factor: 11.454

6.  Detection of treatment-resistant infectious HIV after genome-directed antiviral endonuclease therapy.

Authors:  Harshana S De Silva Feelixge; Daniel Stone; Harlan L Pietz; Pavitra Roychoudhury; Alex L Greninger; Joshua T Schiffer; Martine Aubert; Keith R Jerome
Journal:  Antiviral Res       Date:  2015-12-22       Impact factor: 5.970

7.  In vivo disruption of latent HSV by designer endonuclease therapy.

Authors:  Martine Aubert; Emily A Madden; Michelle Loprieno; Harshana S DeSilva Feelixge; Laurence Stensland; Meei-Li Huang; Alexander L Greninger; Pavitra Roychoudhury; Nixon Niyonzima; Thuy Nguyen; Amalia Magaret; Roman Galleto; Daniel Stone; Keith R Jerome
Journal:  JCI Insight       Date:  2016-09-08

8.  CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape.

Authors:  Zhen Wang; Qinghua Pan; Patrick Gendron; Weijun Zhu; Fei Guo; Shan Cen; Mark A Wainberg; Chen Liang
Journal:  Cell Rep       Date:  2016-04-07       Impact factor: 9.423

9.  Generation of HIV latency in humanized BLT mice.

Authors:  Paul W Denton; Rikke Olesen; Shailesh K Choudhary; Nancy M Archin; Angela Wahl; Michael D Swanson; Morgan Chateau; Tomonori Nochi; John F Krisko; Rae Ann Spagnuolo; David M Margolis; J Victor Garcia
Journal:  J Virol       Date:  2011-10-19       Impact factor: 5.103

10.  CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape.

Authors:  Gang Wang; Na Zhao; Ben Berkhout; Atze T Das
Journal:  Mol Ther       Date:  2016-01-22       Impact factor: 11.454
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  1 in total

Review 1.  Toward the Cure of HIV-1 Infection: Lessons Learned and Yet to be Learned as New Strategies are Developed.

Authors:  Jeffrey M Jacobson; Kamel Khalili
Journal:  AIDS Rev       Date:  2018       Impact factor: 2.500
  1 in total

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