Literature DB >> 2845979

Saposin D: a sphingomyelinase activator.

S Morimoto1, B M Martin, Y Kishimoto, J S O'Brien.   

Abstract

Saposin D, a newly discovered heat-stable, 10 kDa glycoprotein, was isolated from Gaucher spleen and purified to homogeneity. Chemical sequencing from its amino terminus demonstrated colinearity between its amino acid sequence and the deduced amino acid sequence of the fourth domain of prosaposin, the precursor of saposin proteins. Saposin D specifically stimulates acid sphingomyelinase but has no significant effect on the other hydrolases tested.

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Year:  1988        PMID： 2845979     DOI： 10.1016/s0006-291x(88)80855-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  30 in total

1.  Evidence for two cDNA clones encoding human GM2-activator protein.

Authors:  S Nagarajan; H C Chen; S C Li; Y T Li; J M Lockyer
Journal:  Biochem J       Date:  1992-03-15       Impact factor: 3.857

2.  Cholesterol in negatively charged lipid bilayers modulates the effect of the antimicrobial protein granulysin.

Authors:  Hanna Barman; Michael Walch; Sonja Latinovic-Golic; Claudia Dumrese; Max Dolder; Peter Groscurth; Urs Ziegler
Journal:  J Membr Biol       Date:  2007-01-06       Impact factor: 1.843

3.  Cloning, expression and map assignment of chicken prosaposin.

Authors:  N Azuma; H C Seo; O Lie; Q Fu; R M Gould; M Hiraiwa; D W Burt; I R Paton; D R Morrice; J S O'Brien; Y Kishimoto
Journal:  Biochem J       Date:  1998-02-15       Impact factor: 3.857

Review 4.  The protective role of prosaposin and its receptors in the nervous system.

Authors:  Rebecca C Meyer; Michelle M Giddens; Brilee M Coleman; Randy A Hall
Journal:  Brain Res       Date:  2014-08-15       Impact factor: 3.252

5.  Saposin A: second cerebrosidase activator protein.

Authors:  S Morimoto; B M Martin; Y Yamamoto; K A Kretz; J S O'Brien; Y Kishimoto
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

6.  Distribution of saposin proteins (sphingolipid activator proteins) in lysosomal storage and other diseases.

Authors:  S Morimoto; Y Yamamoto; J S O'Brien; Y Kishimoto
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

7.  Synthesis and characterization of a bioactive 82-residue sphingolipid activator protein, saposin C.

Authors:  S Weiler; W Carson; Y Lee; D B Teplow; Y Kishimoto; J S O'Brien; J A Barranger; J M Tomich
Journal:  J Mol Neurosci       Date:  1993       Impact factor: 3.444

8.  Correction of sulfatide metabolism after transfer of prosaposin cDNA to cultured cells from a patient with SAP-1 deficiency.

Authors:  M A Rafi; S Amini; X L Zhang; D A Wenger
Journal:  Am J Hum Genet       Date:  1992-06       Impact factor: 11.025

9.  A stretch of 17 amino acids in the prosaposin C terminus is critical for its binding to sortilin and targeting to lysosomes.

Authors:  Libin Yuan; Carlos R Morales
Journal:  J Histochem Cytochem       Date:  2009-11-24       Impact factor: 2.479

10.  Distribution of saposins (sphingolipid activator proteins) in tissues of lysosomal storage disease patients.

Authors:  M Tayama; J S O'Brien; Y Kishimoto
Journal:  J Mol Neurosci       Date:  1992       Impact factor: 3.444
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