| Literature DB >> 28454979 |
Ina G Panova1, Marina A Yakovleva2, Alexander S Tatikolov2, A S Kononikhin3, Tatiana B Feldman4, Rimma A Poltavtseva5, E N Nikolaev6, Gennady T Sukhikh5, Mikhail A Ostrovsky4.
Abstract
The presence of carotenoids in the vitreous body, retina, lens, retinal pigment epithelium together with choroid (hereinafter RPE), and ciliary body and iris together with choroidal stroma (hereinafter CBI) was studied throughout the second trimester of prenatal development of the human eye. It has been found that the vitreous body, retina, and RPE contain lutein and its oxidized forms. Zeaxanthin was not found in the tissues studied. The presence of lutein in the vitreous body is transient and no longer detected after 28 weeks of gestation. Lutein was not detected in the lens and CBI, but its oxidized forms were found. The presence of carotenoids in different tissues of the eye in the course of normal eye development and the antioxidant role of carotenoids are discussed.Entities:
Keywords: Ciliary body and iris with stroma; Human fetal eye; Lens; Lutein; Lutein oxidized forms; Retina; Retinal pigment epithelium with choroid; Vitreous
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Year: 2017 PMID： 28454979 DOI： 10.1016/j.exer.2017.04.008
Source DB: PubMed Journal: Exp Eye Res ISSN： 0014-4835 Impact factor: 3.467