Literature DB >> 2845275

The HIV tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic mice.

J Vogel1, S H Hinrichs, R K Reynolds, P A Luciw, G Jay.   

Abstract

When the human immunodeficiency virus transactivating gene under the control of the viral regulatory region is introduced into the germline of mice, skin lesions are induced that resemble Kaposi's sarcoma seen in AIDS. Our findings indicate that HIV could play a direct part in causing cancer.

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Year:  1988        PMID： 2845275     DOI： 10.1038/335606a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  112 in total

1.  Contradictory Concepts in the Etiology and Regression of Kaposi's Sarcoma. The Ferenc Györkey Memorial Lecture.

Authors:  Joseph G Sinkovics
Journal:  Pathol Oncol Res       Date:  1996       Impact factor: 3.201

Review 2.  In vitro and animal models of human immunodeficiency virus infection of the central nervous system.

Authors:  Chadd E Nesbit; Stanley A Schwartz
Journal:  Clin Diagn Lab Immunol       Date:  2002-05

3.  Enhancement of chemical hepatocarcinogenesis by the HIV-1 tat gene.

Authors:  G Altavilla; A Caputo; M Lanfredi; C Piola; G Barbanti-Brodano; A Corallini
Journal:  Am J Pathol       Date:  2000-10       Impact factor: 4.307

4.  Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells.

Authors:  J P Taylor; C Cupp; A Diaz; M Chowdhury; K Khalili; S A Jimenez; S Amini
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

5.  HIV-associated Kaposi's sarcoma: new developments in epidemiology and molecular pathology.

Authors:  W K Roth
Journal:  J Cancer Res Clin Oncol       Date:  1991       Impact factor: 4.553

6.  Motility induced by human immunodeficiency virus-1 Tat on Kaposi's sarcoma cells requires platelet-activating factor synthesis.

Authors:  L Biancone; V Cantaluppi; M Boccellino; B Bussolati; L Del Sorbo; P G Conaldi; A Albini; A Toniolo; G Camussi
Journal:  Am J Pathol       Date:  1999-11       Impact factor: 4.307

7.  Identification of specific molecular structures of human immunodeficiency virus type 1 Tat relevant for its biological effects on vascular endothelial cells.

Authors:  S Mitola; R Soldi; I Zanon; L Barra; M I Gutierrez; B Berkhout; M Giacca; F Bussolino
Journal:  J Virol       Date:  2000-01       Impact factor: 5.103

8.  Interactions of the transcription factor AP-1 with the long terminal repeat of different human immunodeficiency virus type 1 strains in Jurkat, glial, and neuronal cells.

Authors:  F Canonne-Hergaux; D Aunis; E Schaeffer
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

9.  Central nervous system-derived cells express a kappa B-binding activity that enhances human immunodeficiency virus type 1 transcription in vitro and facilitates TAR-independent transactivation by Tat.

Authors:  J P Taylor; R J Pomerantz; G V Raj; F Kashanchi; J N Brady; S Amini; K Khalili
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

Review 10.  Kaposi's sarcoma in HIV infected women in Germany: more evidence for sexual transmission. A report of 10 cases and review of the literature.

Authors:  H Albrecht; E B Helm; A Plettenberg; C Emminger; W Heise; B Schwartländer; H J Stellbrink
Journal:  Genitourin Med       Date:  1994-12
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