Literature DB >> 2844236

Chromatin domain surrounding the human interferon-beta gene as defined by scaffold-attached regions.

J Bode1, K Maass.   

Abstract

Regions attached to the nuclear scaffold have been traced after transfecting a 36-kilobase (kb) piece of DNA, surrounding the human interferon-beta gene, into mouse L-cells. An extended attached region starts 1.7 kb upstream from the gene and a moderate binding site immediately downstream. These findings could be confirmed by reconstitution experiments in vitro which predict another scaffold-attached region (SAR) starting 12 kb downstream from the gene. Since no other transcripts originate from DNA between the major SARs, these elements could be involved in interferon gene regulation.

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Year:  1988        PMID： 2844236     DOI： 10.1021/bi00413a019

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


  44 in total

1.  Nuclear scaffolds and scaffold-attachment regions in higher plants.

Authors:  G Hall; G C Allen; D S Loer; W F Thompson; S Spiker
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-15       Impact factor: 11.205

Review 2.  Use of matrix attachment regions (MARs) to minimize transgene silencing.

Authors:  G C Allen; S Spiker; W F Thompson
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

3.  Molecular structure and regulatory potential of a T-DNA integration site in petunia.

Authors:  Antje Dietz-Pfeilstetter; Nicola Arndt; Volker Kay; Jürgen Bode
Journal:  Transgenic Res       Date:  2003-02       Impact factor: 2.788

4.  Evaluation of sequence motifs found in scaffold/matrix-attached regions (S/MARs).

Authors:  I Liebich; J Bode; I Reuter; E Wingender
Journal:  Nucleic Acids Res       Date:  2002-08-01       Impact factor: 16.971

5.  Nuclear matrix attachment occurs in several regions of the IgH locus.

Authors:  P N Cockerill
Journal:  Nucleic Acids Res       Date:  1990-05-11       Impact factor: 16.971

6.  Sequence-specific DNA-binding proteins are components of a nuclear matrix-attachment site.

Authors:  S I Dworetzky; K L Wright; E G Fey; S Penman; J B Lian; J L Stein; G S Stein
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

7.  Supragenic loop organization: mapping in Drosophila embryos, of scaffold-associated regions on a 800 kilobase DNA continuum cloned from the 14B-15B first chromosome region.

Authors:  P Surdej; C Got; R Rosset; R Miassod
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

8.  Breakpoint junctions of chromosome 9p deletions in two human glioma cell lines.

Authors:  H M Pomykala; S K Bohlander; P L Broeker; O I Olopade; M O Díaz
Journal:  Mol Cell Biol       Date:  1994-11       Impact factor: 4.272

9.  Nuclear matrix attachment regions of human papillomavirus type 16 point toward conservation of these genomic elements in all genital papillomaviruses.

Authors:  S H Tan; D Bartsch; E Schwarz; H U Bernard
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

10.  DNA-PK-dependent binding of DNA ends to plasmids containing nuclear matrix attachment region DNA sequences: evidence for assembly of a repair complex.

Authors:  Stanley K Mauldin; Robert C Getts; Wenjing Liu; Thomas D Stamato
Journal:  Nucleic Acids Res       Date:  2002-09-15       Impact factor: 16.971
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