Literature DB >> 28435522

The Ecstasy and Agony of Assay Interference Compounds.

Courtney Aldrich1, Carolyn Bertozzi2, Gunda I Georg3, Laura Kiessling4, Craig Lindsley5, Dennis Liotta6, Kenneth M Merz7, Alanna Schepartz8, Shaomeng Wang3.   

Abstract

Year:  2017        PMID： 28435522      PMCID： PMC5392755          DOI： 10.1021/acsmedchemlett.7b00056

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.345


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  41 in total

1.  A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening.

Authors:  Susan L McGovern; Emilia Caselli; Nikolaus Grigorieff; Brian K Shoichet
Journal:  J Med Chem       Date:  2002-04-11       Impact factor: 7.446

Review 2.  Designing screens: how to make your hits a hit.

Authors:  W Patrick Walters; Mark Namchuk
Journal:  Nat Rev Drug Discov       Date:  2003-04       Impact factor: 84.694

Review 3.  Screening in a spirit haunted world.

Authors:  Brian K Shoichet
Journal:  Drug Discov Today       Date:  2006-07       Impact factor: 7.851

4.  A detergent-based assay for the detection of promiscuous inhibitors.

Authors:  Brian Y Feng; Brian K Shoichet
Journal:  Nat Protoc       Date:  2006       Impact factor: 13.491

5.  New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays.

Authors:  Jonathan B Baell; Georgina A Holloway
Journal:  J Med Chem       Date:  2010-04-08       Impact factor: 7.446

6.  Chemistry: Chemical con artists foil drug discovery.

Authors:  Jonathan Baell; Michael A Walters
Journal:  Nature       Date:  2014-09-25       Impact factor: 49.962

7.  Chemical probes of UDP-galactopyranose mutase.

Authors:  Erin E Carlson; John F May; Laura L Kiessling
Journal:  Chem Biol       Date:  2006-08

8.  Firefly luciferase in chemical biology: a compendium of inhibitors, mechanistic evaluation of chemotypes, and suggested use as a reporter.

Authors:  Natasha Thorne; Min Shen; Wendy A Lea; Anton Simeonov; Scott Lovell; Douglas S Auld; James Inglese
Journal:  Chem Biol       Date:  2012-08-24

9.  Colloidal aggregation affects the efficacy of anticancer drugs in cell culture.

Authors:  Shawn C Owen; Allison K Doak; Pascal Wassam; Molly S Shoichet; Brian K Shoichet
Journal:  ACS Chem Biol       Date:  2012-06-08       Impact factor: 5.100

Review 10.  Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?

Authors:  Jonathan Bisson; James B McAlpine; J Brent Friesen; Shao-Nong Chen; James Graham; Guido F Pauli
Journal:  J Med Chem       Date:  2015-10-27       Impact factor: 7.446
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  10 in total

1.  DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors.

Authors:  Keisuke Tomohara; Isao Adachi; Yoshikazu Horino; Hitoshi Kesamaru; Hitoshi Abe; Keitaro Suyama; Takeru Nose
Journal:  ACS Med Chem Lett       Date:  2019-05-10       Impact factor: 4.345

2.  Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella.

Authors:  Xiang-Na Guan; Tao Zhang; Teng Yang; Ze Dong; Song Yang; Lefu Lan; Jianhua Gan; Cai-Guang Yang
Journal:  RSC Med Chem       Date:  2021-11-01

3.  Inhibitors of HIV-1 Nef-Mediated Activation of the Myeloid Src-Family Kinase Hck Block HIV-1 Replication in Macrophages and Disrupt MHC-I Downregulation.

Authors:  Lori A Emert-Sedlak; Omar Moukha-Chafiq; Haibin Shi; Shoucheng Du; John J Alvarado; Vibha Pathak; Samuel G Tanner; Robert N Hunter; Miranda Nebane; Li Chen; Tatiana V Ilina; Rieko Ishima; Sixue Zhang; Yury V Kuzmichev; Elizabeth R Wonderlich; Susan M Schader; Corinne E Augelli-Szafran; Roger G Ptak; Thomas E Smithgall
Journal:  ACS Infect Dis       Date:  2022-01-05       Impact factor: 5.578

Review 4.  Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017-Utility and Limitations.

Authors:  Jonathan B Baell; J Willem M Nissink
Journal:  ACS Chem Biol       Date:  2017-12-26       Impact factor: 5.100

5.  Quantifying the Interactions between Biomolecules: Guidelines for Assay Design and Data Analysis.

Authors:  Peter J Tonge
Journal:  ACS Infect Dis       Date:  2019-04-13       Impact factor: 5.084

6.  Exploration of icariin analog structure space reveals key features driving potent inhibition of human phosphodiesterase-5.

Authors:  Yasmin Chau; Fu-Shuang Li; Olesya Levsh; Jing-Ke Weng
Journal:  PLoS One       Date:  2019-09-20       Impact factor: 3.240

7.  Novel Immune Modulators Enhance Caenorhabditis elegans Resistance to Multiple Pathogens.

Authors:  Nicholas A Hummell; Alexey V Revtovich; Natalia V Kirienko
Journal:  mSphere       Date:  2021-01-06       Impact factor: 4.389

8.  Discovery of Highly Potent Fusion Inhibitors with Potential Pan-Coronavirus Activity That Effectively Inhibit Major COVID-19 Variants of Concern (VOCs) in Pseudovirus-Based Assays.

Authors:  Francesca Curreli; Shahad Ahmed; Sofia M B Victor; Aleksandra Drelich; Siva S Panda; Andrea Altieri; Alexander V Kurkin; Chien-Te K Tseng; Christopher D Hillyer; Asim K Debnath
Journal:  Viruses       Date:  2021-12-31       Impact factor: 5.048

Review 9.  1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis.

Authors:  Ruan Carlos B Ribeiro; Patricia G Ferreira; Amanda de A Borges; Luana da S M Forezi; Fernando de Carvalho da Silva; Vitor F Ferreira
Journal:  Beilstein J Org Chem       Date:  2022-01-05       Impact factor: 2.883

10.  A Dual-Specificity Inhibitor Targets Polyphosphate Kinase 1 and 2 Enzymes To Attenuate Virulence of Pseudomonas aeruginosa.

Authors:  Nolan Neville; Nathan Roberge; Xiang Ji; Preyesh Stephen; Jiasheng Louis Lu; Zongchao Jia
Journal:  mBio       Date:  2021-06-15       Impact factor: 7.867
  10 in total

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