Literature DB >> 28433510

Biomaterial stiffness determines stem cell fate.

Hongwei Lv1, Heping Wang2, Zhijun Zhang3, Wang Yang3, Wenbin Liu3, Yulin Li4, Lisha Li5.   

Abstract

Stem cells have potential to develop into numerous cell types, thus they are good cell source for tissue engineering. As an external physical signal, material stiffness is capable of regulating stem cell fate. Biomaterial stiffness is an important parameter in tissue engineering. We summarize main measurements of material stiffness under different condition, then list and compare three main methods of controlling stiffness (material amount, crosslinking density and photopolymeriztion time) which interplay with one another and correlate with stiffness positively, and current advances in effects of biomaterial stiffness on stem cell fate. We discuss the unsolved problems and future directions of biomaterial stiffness in tissue engineering.
Copyright © 2017. Published by Elsevier Inc.

Keywords:  Differentiation; Stem cells; Stiffness

Mesh:

Substances:

Year:  2017        PMID: 28433510     DOI: 10.1016/j.lfs.2017.04.014

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  17 in total

1.  Nanohydroxyapatite, Nanosilicate-Reinforced Injectable, and Biomimetic Gelatin-Methacryloyl Hydrogel for Bone Tissue Engineering.

Authors:  Zhe Shi; Qiang Zhong; Yuhang Chen; Jian Gao; Xin Pan; Qiang Lian; Rong Chen; Pinkai Wang; Jian Wang; Zhanjun Shi; Hao Cheng
Journal:  Int J Nanomedicine       Date:  2021-08-16

2.  Cytoprotection of Human Progenitor and Stem Cells through Encapsulation in Alginate Templated, Dual Crosslinked Silk and Silk-Gelatin Composite Hydrogel Microbeads.

Authors:  Onur Hasturk; Jordan A Smiley; Miles Arnett; Jugal Kishore Sahoo; Cristian Staii; David L Kaplan
Journal:  Adv Healthc Mater       Date:  2022-06-22       Impact factor: 11.092

3.  Development of Biodegradable Osteopromotive Citrate-Based Bone Putty.

Authors:  Xinyu Tan; Ethan Gerhard; Yuqi Wang; Richard T Tran; Hui Xu; Su Yan; Elias B Rizk; April D Armstrong; Yuxiao Zhou; Jing Du; Xiaochun Bai; Jian Yang
Journal:  Small       Date:  2022-06-19       Impact factor: 15.153

4.  Photo-tunable hydrogel mechanical heterogeneity informed by predictive transport kinetics model.

Authors:  Callie I Higgins; Jason P Killgore; Frank W DelRio; Stephanie J Bryant; Robert R McLeod
Journal:  Soft Matter       Date:  2020-03-23       Impact factor: 3.679

5.  Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5.

Authors:  Meiyu Sun; Guangfan Chi; Juanjuan Xu; Ye Tan; Jiayi Xu; Shuang Lv; Ziran Xu; Yuhan Xia; Lisha Li; Yulin Li
Journal:  Stem Cell Res Ther       Date:  2018-03-01       Impact factor: 6.832

Review 6.  Adipose Stem Cell Translational Applications: From Bench-to-Bedside.

Authors:  Chiara Argentati; Francesco Morena; Martina Bazzucchi; Ilaria Armentano; Carla Emiliani; Sabata Martino
Journal:  Int J Mol Sci       Date:  2018-11-05       Impact factor: 5.923

7.  The Role of Substrate Topography and Stiffness on MSC Cells Functions: Key Material Properties for Biomimetic Bone Tissue Engineering.

Authors:  Foteini K Kozaniti; Despina D Deligianni; Margarita D Georgiou; Diana V Portan
Journal:  Biomimetics (Basel)       Date:  2021-12-31

Review 8.  Collagen Scaffolds in Cartilage Tissue Engineering and Relevant Approaches for Future Development.

Authors:  Vincent Irawan; Tzu-Cheng Sung; Akon Higuchi; Toshiyuki Ikoma
Journal:  Tissue Eng Regen Med       Date:  2018-07-25       Impact factor: 4.169

Review 9.  The Application of Stem Cells from Different Tissues to Cartilage Repair.

Authors:  James N Fisher; Irene Tessaro; Tommaso Bertocco; Giuseppe M Peretti; Laura Mangiavini
Journal:  Stem Cells Int       Date:  2017-12-10       Impact factor: 5.443

Review 10.  Proteins and Peptides as Important Modifiers of the Polymer Scaffolds for Tissue Engineering Applications-A Review.

Authors:  Katarzyna Klimek; Grazyna Ginalska
Journal:  Polymers (Basel)       Date:  2020-04-06       Impact factor: 4.329

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