Literature DB >> 28432506

Elective Colectomy for Diverticulitis in Transplant Patients: Is It Worth the Risk?

Janet T Lee1, Steve Skube1, Genevieve B Melton1, Mary R Kwaan1, Christine C Jensen1, Robert D Madoff1, Wolfgang B Gaertner2.   

Abstract

BACKGROUND: The aim of this study was to determine morbidity and mortality for transplant patients undergoing elective colectomy for diverticulitis and determine the impact of recurrent diverticulitis on postoperative complications.
METHODS: We identified transplant recipients that underwent elective colectomy for diverticulitis between 2000 and 2015 at a tertiary care institution. Patient and procedure variables, postoperative complications, length of stay, 30-day readmission, and mortality were identified through retrospective chart review. Complication rates were compared between patients with one previous episode of diverticulitis versus two or more.
RESULTS: Thirty transplant recipients underwent colectomy for primary (n = 13) or recurrent (n = 17) diverticulitis. Primary anastomosis was performed in 26 (87%) with proximal diversion in 10 (38%). The overall complication rate was 57%, with surgical site infection being the most common (23%). There were no anastomotic leaks at the colorectal anastomosis or reoperations. Median length of stay was 8 days (range 4-23). Postoperative complications were not significantly different between groups (54 vs. 59%, p = 0.94).
CONCLUSIONS: Postoperative morbidity after elective colectomy for diverticulitis in transplant recipients was common. There were no differences in complications for patients with primary versus recurrent diverticulitis. Fear of postoperative complications from recurrent diverticulitis should not be a reason to recommend elective colectomy after an initial attack of diverticulitis in transplant patients.

Entities:  

Keywords:  Diverticulitis; Elective surgery; Solid organ transplant

Mesh:

Year:  2017        PMID: 28432506     DOI: 10.1007/s11605-017-3432-z

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  6 in total

1.  Laparoscopic sigmoid resection for diverticulitis decreases major morbidity rates: a randomized control trial: short-term results of the Sigma Trial.

Authors:  Bastiaan R Klarenbeek; Alexander A Veenhof; Roberto Bergamaschi; Donald L van der Peet; Wim T van den Broek; Elly S de Lange; Willem A Bemelman; Piet Heres; Antonio M Lacy; Alexander F Engel; Miguel A Cuesta
Journal:  Ann Surg       Date:  2009-01       Impact factor: 12.969

2.  Recurrence and virulence of colonic diverticulitis in immunocompromised patients.

Authors:  Sebastiano Biondo; Jaime Lopez Borao; Esther Kreisler; Thomas Golda; Monica Millan; Ricardo Frago; Domenico Fraccalvieri; Jordi Guardiola; Eduardo Jaurrieta
Journal:  Am J Surg       Date:  2012-03-23       Impact factor: 2.565

Review 3.  A systematic review of complicated diverticulitis in post-transplant patients.

Authors:  J E Oor; J J Atema; M A Boermeester; B C Vrouenraets; Ç Ünlü
Journal:  J Gastrointest Surg       Date:  2014-08-16       Impact factor: 3.452

Review 4.  Diverticulitis in transplant patients and patients on chronic corticosteroid therapy: a systematic review.

Authors:  Stephanie S Hwang; Rebecca R Cannom; Maher A Abbas; David Etzioni
Journal:  Dis Colon Rectum       Date:  2010-12       Impact factor: 4.585

5.  Case-matched comparison of perioperative outcomes after surgical treatment of sigmoid diverticulitis in solid organ transplant recipients versus immunocompetent patients.

Authors:  A Reshef; L Stocchi; R P Kiran; S Flechner; M Budev; C Quintini; F H Remzi
Journal:  Colorectal Dis       Date:  2012-12       Impact factor: 3.788

6.  NLP-PIER: A Scalable Natural Language Processing, Indexing, and Searching Architecture for Clinical Notes.

Authors:  Reed McEwan; Genevieve B Melton; Benjamin C Knoll; Yan Wang; Gretchen Hultman; Justin L Dale; Tim Meyer; Serguei V Pakhomov
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2016-07-20
  6 in total
  2 in total

Review 1.  [Diverticulitis : Domain of conservative or drug therapy?]

Authors:  S Böhm; W Kruis
Journal:  Internist (Berl)       Date:  2017-07       Impact factor: 0.743

Review 2.  The Indications for and Timing of Surgery for Diverticular Disease.

Authors:  Johan Friso Lock; Christian Galata; Christoph Reißfelder; Jörg-Peter Ritz; Thomas Schiedeck; Christoph-Thomas Germer
Journal:  Dtsch Arztebl Int       Date:  2020-08-31       Impact factor: 5.594

  2 in total

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