Literature DB >> 28608124

[Diverticulitis : Domain of conservative or drug therapy?]

S Böhm1, W Kruis2.   

Abstract

Increasing interest in diverticular disease by the scientific community in the last 10-15 years has resulted in an increased number of publications. Among other things, nonevidence-based therapeutic paradigms were tested in randomized, controlled therapy studies. The importance of surgery in the therapy of diverticulitis has diminished in recent years; in particular, it has no role in the treatment of diverticulitis types 1a, 1b, and 2a according to the Classification of Diverticular Disease (CDD) treated successfully by conservative means. Surgery has only a subordinate role in recurrent type 3b diverticulitis according to the CDD. Diverticulitis is therefore increasingly treated using conservative or drug therapy. However, only the classic, established antibiotics are currently available as effective drugs for the treatment of diverticular disease. However, these are also decreasing in significance. Over 90% of patients with type 1a/1b diverticulitis can be safely treated according to current data without the use of antibiotics. It is possible that type 2a diverticulitis will also be successfully treated without antibiotics in the future. Substances such as rifaximin, mesalazine, or probiotics, which were tested above all in patients with chronic recurrent forms (CDD type 3a/3b), have not yet been established.

Entities:  

Keywords:  Antibiotics; Diverticulitis, classification; Mesalazine; Probiotics; Rifaximin

Mesh:

Substances:

Year:  2017        PMID: 28608124     DOI: 10.1007/s00108-017-0266-4

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  41 in total

1.  American Gastroenterological Association Institute Guideline on the Management of Acute Diverticulitis.

Authors:  Neil Stollman; Walter Smalley; Ikuo Hirano
Journal:  Gastroenterology       Date:  2015-10-08       Impact factor: 22.682

Review 2.  Clinical practice. Diverticulitis.

Authors:  Danny O Jacobs
Journal:  N Engl J Med       Date:  2007-11-15       Impact factor: 91.245

Review 3.  Burden of digestive diseases in the United States part I: overall and upper gastrointestinal diseases.

Authors:  James E Everhart; Constance E Ruhl
Journal:  Gastroenterology       Date:  2009-01-03       Impact factor: 22.682

Review 4.  Lifestyle and other risk factors for diverticulitis.

Authors:  Stephan K Böhm; Wolfgang Kruis
Journal:  Minerva Gastroenterol Dietol       Date:  2017-02-01

5.  Mild colonic diverticulitis can be treated without antibiotics. A case-control study.

Authors:  N de Korte; J Ph Kuyvenhoven; D L van der Peet; R J Felt-Bersma; M A Cuesta; H B A C Stockmann
Journal:  Colorectal Dis       Date:  2012-03       Impact factor: 3.788

6.  Randomised clinical trial: mesalazine (Salofalk granules) for uncomplicated diverticular disease of the colon--a placebo-controlled study.

Authors:  W Kruis; E Meier; M Schumacher; O Mickisch; R Greinwald; R Mueller
Journal:  Aliment Pharmacol Ther       Date:  2013-02-17       Impact factor: 8.171

7.  [S2k guidelines diverticular disease/diverticulitis].

Authors:  L Leifeld; C T Germer; S Böhm; F L Dumoulin; W Häuser; M Kreis; J Labenz; B Lembcke; S Post; M Reinshagen; J-P Ritz; T Sauerbruch; T Wedel; B von Rahden; W Kruis
Journal:  Z Gastroenterol       Date:  2014-07-15       Impact factor: 2.000

Review 8.  Probiotics in the Treatment of Diverticular Disease. A Systematic Review.

Authors:  Edith Lahner; Cristina Bellisario; Cesare Hassan; Angelo Zullo; Gianluca Esposito; Bruno Annibale
Journal:  J Gastrointestin Liver Dis       Date:  2016-03       Impact factor: 2.008

Review 9.  Guidelines of diagnostics and treatment of acute left-sided colonic diverticulitis.

Authors:  Caroline S Andeweg; Irene M Mulder; Richelle J F Felt-Bersma; Annelies Verbon; Gert Jan van der Wilt; Harry van Goor; Johan F Lange; Jaap Stoker; Marja A Boermeester; Robert P Bleichrodt
Journal:  Dig Surg       Date:  2013-08-20       Impact factor: 2.588

10.  Long-term follow-up and development of diverticulitis in patients diagnosed with diverticulosis of the colon.

Authors:  R J L F Loffeld
Journal:  Int J Colorectal Dis       Date:  2015-09-26       Impact factor: 2.571

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  1 in total

Review 1.  Excessive Body Weight and Diverticular Disease.

Authors:  Stephan K Böhm
Journal:  Visc Med       Date:  2021-09-15
  1 in total

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