Literature DB >> 2842729

Insertion of a retrotransposon within the 3' end of a mouse gene provides a new functional polyadenylation signal.

T Baumruker1, C Gehe, I Horak.   

Abstract

A site of genomic insertion of the mouse retrotransposon LTR-IS/MuRRS was analysed. The comparison of the genomic and the cDNA clones indicates the insertion of the LTR-IS element into the 3' untranslated region of a mouse gene. The fact that the isolated cDNA clone ends with a poly A tail 20 nucleotides downstream from the LTR-IS AATAAA box and the result of the S1-nuclease mapping provides evidence that the 3' end of the mouse gene transcript was generated under the control of the LTR-IS polyadenylation signal.

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Year:  1988        PMID: 2842729      PMCID: PMC338406          DOI: 10.1093/nar/16.15.7241

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  24 in total

1.  Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

2.  A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation.

Authors:  G Shaw; R Kamen
Journal:  Cell       Date:  1986-08-29       Impact factor: 41.582

3.  A simple and very efficient method for generating cDNA libraries.

Authors:  U Gubler; B J Hoffman
Journal:  Gene       Date:  1983-11       Impact factor: 3.688

4.  The Notch locus of Drosophila melanogaster.

Authors:  S Kidd; T J Lockett; M W Young
Journal:  Cell       Date:  1983-09       Impact factor: 41.582

5.  Multiple 3' ends of the chicken pro alpha 2(I) collagen gene.

Authors:  S Aho; V Tate; H Boedtker
Journal:  Nucleic Acids Res       Date:  1983-08-25       Impact factor: 16.971

6.  Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis.

Authors:  W S Hayward; B G Neel; S M Astrin
Journal:  Nature       Date:  1981-04-09       Impact factor: 49.962

7.  A Drosophila metabolic gene transcript is alternatively processed.

Authors:  S Henikoff; J S Sloan; J D Kelly
Journal:  Cell       Date:  1983-09       Impact factor: 41.582

8.  Family of middle repetitive DNA sequences in the mouse genome with structural features of solitary retroviral long terminal repeats.

Authors:  T Wirth; K Glöggler; T Baumruker; M Schmidt; I Horak
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205

9.  Alpha-thalassaemia caused by a polyadenylation signal mutation.

Authors:  D R Higgs; S E Goodbourn; J Lamb; J B Clegg; D J Weatherall; N J Proudfoot
Journal:  Nature       Date:  1983 Nov 24-30       Impact factor: 49.962

10.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Authors:  J M Chirgwin; A E Przybyla; R J MacDonald; W J Rutter
Journal:  Biochemistry       Date:  1979-11-27       Impact factor: 3.162

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  2 in total

Review 1.  Reverse transcriptase: mediator of genomic plasticity.

Authors:  J Brosius; H Tiedge
Journal:  Virus Genes       Date:  1995       Impact factor: 2.332

2.  Stowaway: a new family of inverted repeat elements associated with the genes of both monocotyledonous and dicotyledonous plants.

Authors:  T E Bureau; S R Wessler
Journal:  Plant Cell       Date:  1994-06       Impact factor: 11.277

  2 in total

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