Tair Ben-Porat1, Ram Elazary2, Ariela Goldenshluger3, Shiri Sherf Dagan4, Yoav Mintz2, Ram Weiss5. 1. Department of Nutrition, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. Electronic address: tairbp20@gmail.com. 2. Department of Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. 3. Department of Nutrition, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. 4. Department of Nutrition, Assuta Medical Center, Tel Aviv, Israel. 5. Department of Human Metabolism and Nutrition, Hebrew University, Jerusalem, Israel.
Abstract
BACKGROUND: Data regarding long-term nutritional deficiencies following laparoscopic sleeve gastrectomy (LSG) are scarce. OBJECTIVES: To assess the prevalence of nutritional deficiencies and supplement consumption 4 years post-LSG. SETTING: Hebrew University, Israel. METHODS: Data were collected prospectively from preoperative and 1 and 4 years postoperative including anthropometric parameters, biochemical tests, and supplement intake. RESULTS: Data were available for 192, 77, and 27 patients at presurgery and 1 and 4 years post-LSG, respectively. Prevalence of nutritional deficiencies at baseline and 1 and 4 years postsurgery, respectively, were specifically for iron (44%, 41.2%, 28.6%), anemia (11.5%, 20%, 18.5%), folate (46%, 14.3%, 12.5%), vitamin B12 (7.7%, 13.6%, 15.4%), vitamin D (96.2%, 89%, 86%), and elevated parathyroid hormone (PTH) (52%, 15.4%, 60%). Vitamin D levels remained low throughout the whole period. PTH levels were 37.5 pg/mL at 1 year postsurgery and increased to 77.3 pg/mL at 4 years postsurgery (P = .009). Females had higher prevalence of elevated PTH and a tendency for higher rates of anemia, compared with males 4 years postsurgery (80% versus 20%, P = .025; and 28% versus 0%, P = .08, respectively). Of the patients, 92.6% reported taking a multivitamin and 74.1% vitamin D supplements during the first postoperative year, while after 4 years only 37% and 11.1% were still taking these supplements, respectively. CONCLUSION: A high rate of nutritional deficiencies is common at 4 years post-LSG along with low adherence to the nutritional supplementation regimen. Long-term nutritional follow-up and supplementation maintenance are crucial for LSG patients. Future studies are needed to clarify the clinical impact of such deficiencies.
BACKGROUND: Data regarding long-term nutritional deficiencies following laparoscopic sleeve gastrectomy (LSG) are scarce. OBJECTIVES: To assess the prevalence of nutritional deficiencies and supplement consumption 4 years post-LSG. SETTING: Hebrew University, Israel. METHODS: Data were collected prospectively from preoperative and 1 and 4 years postoperative including anthropometric parameters, biochemical tests, and supplement intake. RESULTS: Data were available for 192, 77, and 27 patients at presurgery and 1 and 4 years post-LSG, respectively. Prevalence of nutritional deficiencies at baseline and 1 and 4 years postsurgery, respectively, were specifically for iron (44%, 41.2%, 28.6%), anemia (11.5%, 20%, 18.5%), folate (46%, 14.3%, 12.5%), vitamin B12 (7.7%, 13.6%, 15.4%), vitamin D (96.2%, 89%, 86%), and elevated parathyroid hormone (PTH) (52%, 15.4%, 60%). Vitamin D levels remained low throughout the whole period. PTH levels were 37.5 pg/mL at 1 year postsurgery and increased to 77.3 pg/mL at 4 years postsurgery (P = .009). Females had higher prevalence of elevated PTH and a tendency for higher rates of anemia, compared with males 4 years postsurgery (80% versus 20%, P = .025; and 28% versus 0%, P = .08, respectively). Of the patients, 92.6% reported taking a multivitamin and 74.1% vitamin D supplements during the first postoperative year, while after 4 years only 37% and 11.1% were still taking these supplements, respectively. CONCLUSION: A high rate of nutritional deficiencies is common at 4 years post-LSG along with low adherence to the nutritional supplementation regimen. Long-term nutritional follow-up and supplementation maintenance are crucial for LSG patients. Future studies are needed to clarify the clinical impact of such deficiencies.
Authors: Seda Sancak; Özgen Çeler; Elif Çırak; Aziz Bora Karip; M Tumiçin Aydın; Nuriye Esenbulut; M Mahir Fersahoğlu; Hasan Altun; Kemal Memişoğlu Journal: Obes Surg Date: 2019-08 Impact factor: 4.129
Authors: Laura Heusschen; Wendy Schijns; Nadine Ploeger; Laura N Deden; Eric J Hazebroek; Frits J Berends; Edo O Aarts Journal: Obes Surg Date: 2020-04 Impact factor: 4.129
Authors: Hendrika J M Smelt; Saskia van Loon; Sjaak Pouwels; Arjen-Kars Boer; Johannes F Smulders; Edo O Aarts Journal: Obes Surg Date: 2020-02 Impact factor: 4.129
Authors: Eva-Christina Krzizek; Johanna Maria Brix; Alexander Stöckl; Verena Parzer; Bernhard Ludvik Journal: Obes Facts Date: 2021-04-01 Impact factor: 3.942
Authors: Ariela Goldenshluger; R Elazary; M J Cohen; M Goldenshluger; T Ben-Porat; J Nowotni; H Geraisi; M Amun; A J Pikarsky; L Keinan-Boker Journal: Obes Surg Date: 2018-10 Impact factor: 4.129