Literature DB >> 2841258

[Antibodies against HTLV I in T-lymphoproliferative diseases of the skin].

D von der Helm1, K von der Helm, G Burg, O Braun-Falco, F Deinhardt.   

Abstract

The possibility that lymphoproliferative diseases may have a viral etiology has been discussed for many years. The first piece of evidence - in combination with convincing epidemiological data - was the detection of a virus of the HTLV group (HTLV I, ATLV) in patients with adult T-cell leukemia in Japan. There have been no comparable observations made in Europe. In 7 of 72 sera of patients with T-lymphoproliferative diseases in Central Europe, we were able to detect antibodies against HTLV I (ELISA and immunoblot), which might be an indication that retroviruses play a role in the etiology of these diseases.

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Year:  1988        PMID: 2841258

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  2 in total

1.  Antibodies against retroviral core proteins in relation to disease outcome in patients with mycosis fungoides.

Authors:  A Ranki; K M Niemi; P Nieminen; K Krohn
Journal:  Arch Dermatol Res       Date:  1990       Impact factor: 3.017

2.  Detection of HTLV-I proviral sequences in CD30-positive large cell cutaneous T-cell lymphomas.

Authors:  I Anagnostopoulos; M Hummel; P Kaudewitz; H Herbst; O Braun-Falco; H Stein
Journal:  Am J Pathol       Date:  1990-12       Impact factor: 4.307

  2 in total

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