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Literature DB >> 2175544

Detection of HTLV-I proviral sequences in CD30-positive large cell cutaneous T-cell lymphomas.

I Anagnostopoulos¹, M Hummel, P Kaudewitz, H Herbst, O Braun-Falco, H Stein.

Abstract

To investigate the possibility that cutaneous T-cell lymphomas of large cell type may be associated with human T-cell leukemia/lymphoma virus type I infection in nonendemic regions, tissue samples from six cases of large cell cutaneous T-cell lymphoma and four cases of small cell cutaneous T-cell lymphoma were screened for the presence of integrated proviral human T-cell leukemia/lymphoma virus type I DNA. Combined use of Southern blot hybridization and enzymatic DNA amplification revealed human T-cell leukemia/lymphoma virus type I-specific sequences in all cases of large cell cutaneous T-cell lymphoma and in none of the cases of small cell cutaneous T-cell lymphoma. These results suggest that in nonendemic areas, a significant proportion of large cell cutaneous T-cell lymphoma cases are associated with human T-cell leukemia/lymphoma virus type I.

Entities: Disease Species

Mesh：

Substances：

Year: 1990 PMID： 2175544 PMCID： PMC1877736

Source DB: PubMed Journal: Am J Pathol ISSN： 0002-9440 Impact factor: 4.307

24 in total

1. Use of freeze-dried paraffin-embedded sections for immunohistologic staining with monoclonal antibodies.

Authors: H Stein; K Gatter; H Asbahr; D Y Mason
Journal: Lab Invest Date: 1985-06 Impact factor: 5.662

2. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

Authors: J L Cordell; B Falini; W N Erber; A K Ghosh; Z Abdulaziz; S MacDonald; K A Pulford; H Stein; D Y Mason
Journal: J Histochem Cytochem Date: 1984-02 Impact factor: 2.479

3. Isolation of a new type C retrovirus (HTLV) in primary uncultured cells of a patient with Sézary T-cell leukaemia.

Authors: B J Poiesz; F W Ruscetti; M S Reitz; V S Kalyanaraman; R C Gallo
Journal: Nature Date: 1981-11-19 Impact factor: 49.962

4. Nucleotide sequence analysis of a variant human T-cell leukemia virus (HTLV-Ib) provirus with a deletion in pX-I.

Authors: L Ratner; S F Josephs; B Starcich; B Hahn; G M Shaw; R C Gallo; F Wong-Staal
Journal: J Virol Date: 1985-06 Impact factor: 5.103

5. Adult T-cell lymphoma-leukaemia in Blacks from the West Indies.

Authors: D Catovsky; M F Greaves; M Rose; D A Galton; A W Goolden; D R McCluskey; J M White; I Lampert; G Bourikas; R Ireland; A I Brownell; J M Bridges; W A Blattner; R C Gallo
Journal: Lancet Date: 1982-03-20 Impact factor: 79.321

6. Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease.

Authors: M Yoshida; M Seiki; K Yamaguchi; K Takatsuki
Journal: Proc Natl Acad Sci U S A Date: 1984-04 Impact factor: 11.205

7. Genomes of evolutionarily divergent members of the human T-cell leukemia virus family (HTLV-I and HTLV-II) are highly conserved, especially in pX.

Authors: G M Shaw; M A Gonda; G H Flickinger; B H Hahn; R C Gallo; F Wong-Staal
Journal: Proc Natl Acad Sci U S A Date: 1984-07 Impact factor: 11.205

8. Human T-cell leukemia virus (HTLV-I) transcripts in fresh and cultured cells of patients with adult T-cell leukemia.

Authors: G Franchini; F Wong-Staal; R C Gallo
Journal: Proc Natl Acad Sci U S A Date: 1984-10 Impact factor: 11.205

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Authors: P A Bunn; G P Schechter; E Jaffe; D Blayney; R C Young; M J Matthews; W Blattner; S Broder; M Robert-Guroff; R C Gallo
Journal: N Engl J Med Date: 1983-08-04 Impact factor: 91.245

10. The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells.

Authors: H Stein; D Y Mason; J Gerdes; N O'Connor; J Wainscoat; G Pallesen; K Gatter; B Falini; G Delsol; H Lemke
Journal: Blood Date: 1985-10 Impact factor: 22.113

4 in total

1. No evidence of HTLV-I proviral integration in lymphoproliferative disorders associated with cutaneous T-cell lymphoma.

Authors: G S Wood; J M Schaffer; R Boni; R Dummer; G Burg; M Takeshita; M Kikuchi
Journal: Am J Pathol Date: 1997-02 Impact factor: 4.307