| Literature DB >> 28411907 |
Robert M Turner1, Todd M Morgan2, Bruce L Jacobs3.
Abstract
The incidence of kidney cancer has steadily increased over recent decades, with most new cases now found when lesions are asymptomatic and small. This downward stage migration relates to the increasing use of abdominal imaging. Three public health epidemics-smoking, hypertension, and obesity-also play roles in the increase. Treatment mirrors the rise in incidence, with increasing interest in nephron-sparing therapies. Despite earlier detection and increasing treatment, the mortality rate has not decreased. This treatment disconnect phenomenon highlights the need to decrease unnecessary treatment of indolent tumors and address modifiable risk factors to reduce incidence and mortality.Entities:
Keywords: Epidemiology; Incidence; Kidney cancer; Mortality; Treatment disconnect
Mesh:
Year: 2017 PMID: 28411907 PMCID: PMC5407311 DOI: 10.1016/j.ucl.2016.12.001
Source DB: PubMed Journal: Urol Clin North Am ISSN: 0094-0143 Impact factor: 2.241