Guldem Turan1, Arzu Yıldırım Ar2, Yıldız Yigit Kuplay2, Oznur Demiroluk2, Mustafa Gazi2, Nur Akgun2, Erhan Celikoglu3. 1. Fatih Sultan Mehmet Teaching and Research Hospital, Anesthesiology and Intensive Care Unit, Istanbul, Turquia. Electronic address: gturanmd@yahoo.com. 2. Fatih Sultan Mehmet Teaching and Research Hospital, Anesthesiology and Intensive Care Unit, Istanbul, Turquia. 3. Fatih Sultan Mehmet Teaching and Research Hospital, Department of Neurosurgery, Istanbul, Turquia.
Abstract
BACKGROUND AND OBJECTIVES: The Analgesia Nociception Index is an index used to measure the levels of pain, sympathetic system activity and heart rate variability during general anesthesia. In our study, Analgesia Nociception Index monitoring in two groups who had undergone spinal stabilization surgery and were administered propofol-remifentanil (Total Intravenous Anesthesia) and sevoflurane-remifentanyl anesthesia was compared regarding its significance for prediction of postoperative early pain. METHODS: BIS and Analgesia Nociception Index monitoring were conducted in the patients together with standard monitoring. During induction, fentanyl 2μg.kg-1, propofol 2.5mg.kg-1 and rocuronium 0.6mg.kg-1 were administered. During maintenance, 1.0 MAC sevoflurane+remifentanil 0.05-0.3μg.kg-1.min-1 and propofol 50-150μg.kg-1.min+remifentanil 0.05-0.3μg.kg-1.min-1 were administered in Group S and Group T, respectively. Hemodynamic parameters, BIS and Analgesia Nociception Index values were recorded during surgery and 30min postoperatively. Postoperative visual analog scale (VAS) values at 30minutes were recorded. RESULTS: While no difference was found between mean Analgesia Nociception Index at all times of measurement in both groups, Analgesia Nociception Index measurements after administration of perioperative analgesic drug were recorded to be significantly higher compared to baseline values in both groups. There was correlation between mean values of Analgesia Nociception Index and VAS after anesthesia. CONCLUSION: Analgesia Nociception Index is a valuable parameter for monitoring of perioperative and postoperative analgesia. In spine surgery, similar analgesia can be provided in both Total Intravenous Anesthesia with remifentanil and sevoflurane administration. Analgesia Nociception Index is efficient for prediction of the need for analgesia during the early postoperative period, and therefore is the provision of patient comfort.
BACKGROUND AND OBJECTIVES: The Analgesia Nociception Index is an index used to measure the levels of pain, sympathetic system activity and heart rate variability during general anesthesia. In our study, Analgesia Nociception Index monitoring in two groups who had undergone spinal stabilization surgery and were administered propofol-remifentanil (Total Intravenous Anesthesia) and sevoflurane-remifentanyl anesthesia was compared regarding its significance for prediction of postoperative early pain. METHODS: BIS and Analgesia Nociception Index monitoring were conducted in the patients together with standard monitoring. During induction, fentanyl 2μg.kg-1, propofol 2.5mg.kg-1 and rocuronium 0.6mg.kg-1 were administered. During maintenance, 1.0 MAC sevoflurane+remifentanil 0.05-0.3μg.kg-1.min-1 and propofol 50-150μg.kg-1.min+remifentanil 0.05-0.3μg.kg-1.min-1 were administered in Group S and Group T, respectively. Hemodynamic parameters, BIS and Analgesia Nociception Index values were recorded during surgery and 30min postoperatively. Postoperative visual analog scale (VAS) values at 30minutes were recorded. RESULTS: While no difference was found between mean Analgesia Nociception Index at all times of measurement in both groups, Analgesia Nociception Index measurements after administration of perioperative analgesic drug were recorded to be significantly higher compared to baseline values in both groups. There was correlation between mean values of Analgesia Nociception Index and VAS after anesthesia. CONCLUSION:Analgesia Nociception Index is a valuable parameter for monitoring of perioperative and postoperative analgesia. In spine surgery, similar analgesia can be provided in both Total Intravenous Anesthesia with remifentanil and sevoflurane administration. Analgesia Nociception Index is efficient for prediction of the need for analgesia during the early postoperative period, and therefore is the provision of patient comfort.
Authors: Vincent So; Marielle Balanaser; Gregory Klar; Jordan Leitch; Michael McGillion; P J Devereaux; Ramiro Arellano; Joel Parlow; Ian Gilron Journal: Pain Rep Date: 2021-12-02
Authors: Mustafa Gazi; Süheyla Abitağaoğlu; Güldem Turan; Ceren Köksal; Fatma Nur Akgün; Dilek E Ari Journal: Saudi Med J Date: 2018-10 Impact factor: 1.484
Authors: Ricardo H Aoki; Italla Maria Pinheiro Bezerra; Alvaro Dantas de Almeida-Júnior; Renata Thaís de A Barbosa; Vitor E Valenti; Fernando R Oliveira; Adriano L Roque; Hugo Macedo Ferraz E Souza Júnior; David M Garner; Rodrigo D Raimundo; Luiz Carlos de Abreu Journal: Clinics (Sao Paulo) Date: 2019-09-09 Impact factor: 2.365