Literature DB >> 28410120

SNP_TATA_Comparator: genomewide landmarks for preventive personalized medicine.

Mikhail Ponomarenko1, Dmitry Rasskazov2, Irina Chadaeva3, Ekaterina Sharypova2, Petr Ponomarenko4, Olga Arkova2, Elena Kashina2, Nikita Ivanisenko2, Dmitry Zhechev2, Ludmila Savinkova2, Nikolay Kolchanov3.   

Abstract

Year after year, conditions, quality, and duration of human lives have been improving due to the progress of science, technology, education, and medicine, which however has a downside. Owing to improvement in children's nutrition, developmental acceleration occurs that imbalances a child's system. Because of virtual worlds of the Internet, social experience of teenagers expands and clashes with puberty of adolescents. Due to the comfort of cities, urbanization emerges and causes stress to adults because of artificial light, noise, pollution, violations of personal space, and family disruption. At old age, all these factors taken together contribute to loneliness, cancer, diabetes, drug addiction, and sporadic Alzheimer's disease, which shorten the lifespan, as reviewed in the US, 1990-2010. That is why, a person may ask oneself: "What can I do now to keep my health in my old age?" To help them, we provide this comprehensive review on predictive preventive personalized medicine. This branch of molecular medicine uses single nucleotide polymorphisms to prevent diseases on the basis of the difference between the individual and reference human genomes.

Entities:  

Mesh:

Year:  2017        PMID: 28410120     DOI: 10.2741/s488

Source DB:  PubMed          Journal:  Front Biosci (Schol Ed)        ISSN: 1945-0516


  5 in total

1.  Candidate SNP Markers of Familial and Sporadic Alzheimer's Diseases Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters.

Authors:  Petr Ponomarenko; Irina Chadaeva; Dmitry A Rasskazov; Ekaterina Sharypova; Elena V Kashina; Irina Drachkova; Dmitry Zhechev; Mikhail P Ponomarenko; Ludmila K Savinkova; Nikolay Kolchanov
Journal:  Front Aging Neurosci       Date:  2017-07-20       Impact factor: 5.750

2.  Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters.

Authors:  Irina V Chadaeva; Petr M Ponomarenko; Dmitry A Rasskazov; Ekaterina B Sharypova; Elena V Kashina; Dmitry A Zhechev; Irina A Drachkova; Olga V Arkova; Ludmila K Savinkova; Mikhail P Ponomarenko; Nikolay A Kolchanov; Ludmila V Osadchuk; Alexandr V Osadchuk
Journal:  BMC Genomics       Date:  2018-02-09       Impact factor: 3.969

3.  Candidate SNP Markers of Atherogenesis Significantly Shifting the Affinity of TATA-Binding Protein for Human Gene Promoters show stabilizing Natural Selection as a Sum of Neutral Drift Accelerating Atherogenesis and Directional Natural Selection Slowing It.

Authors:  Mikhail Ponomarenko; Dmitry Rasskazov; Irina Chadaeva; Ekaterina Sharypova; Irina Drachkova; Dmitry Oshchepkov; Petr Ponomarenko; Ludmila Savinkova; Evgeniya Oshchepkova; Maria Nazarenko; Nikolay Kolchanov
Journal:  Int J Mol Sci       Date:  2020-02-05       Impact factor: 5.923

4.  Unannotated single nucleotide polymorphisms in the TATA box of erythropoiesis genes show in vitro positive involvements in cognitive and mental disorders.

Authors:  Mikhail Ponomarenko; Ekaterina Sharypova; Irina Drachkova; Irina Chadaeva; Olga Arkova; Olga Podkolodnaya; Petr Ponomarenko; Nikolay Kolchanov; Ludmila Savinkova
Journal:  BMC Med Genet       Date:  2020-10-22       Impact factor: 2.103

5.  Disruptive natural selection by male reproductive potential prevents underexpression of protein-coding genes on the human Y chromosome as a self-domestication syndrome.

Authors:  Mikhail Ponomarenko; Maxim Kleshchev; Petr Ponomarenko; Irina Chadaeva; Ekaterina Sharypova; Dmitry Rasskazov; Semyon Kolmykov; Irina Drachkova; Gennady Vasiliev; Natalia Gutorova; Elena Ignatieva; Ludmila Savinkova; Anton Bogomolov; Ludmila Osadchuk; Alexandr Osadchuk; Dmitry Oshchepkov
Journal:  BMC Genet       Date:  2020-10-22       Impact factor: 2.797

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.