Myles M Mitsunaga1, Shannon Kogachi2, Hyo-Chun Yoon3. 1. Diagnostic Radiology Resident in the Department of Radiology at the University of California Davis Medical Center in Sacramento. mylesm@hawaii.edu. 2. Medical Student at the University of Hawaii John A Burns School of Medicine in Honolulu. kogachi@hawaii.edu. 3. Assistant Chief of Diagnostic Imaging for the Hawaii Permanente Medical Group. hyo-chun.yoon@kp.org.
Abstract
CONTEXT: The optimal lower extremity venous ultrasound (US) protocol to diagnose deep venous thrombosis of the popliteal and more proximal veins is unclear. OBJECTIVE: To determine the three-month rate of symptomatic venous thromboembolism (VTE) and clinical outcomes of inpatients and ambulatory patients with normal findings on single venous ultrasound of the popliteal and more proximal veins (single proximal US). DESIGN: Single proximal US results and clinical data of all inpatient and ambulatory patients with suspected acute deep venous thrombosis were retrospectively reviewed during a 12-month period between January and December 2014. Three-month follow-up data were reviewed for all these patients, who received all their care from a single geographically isolated health maintenance organization. MAIN OUTCOME MEASURES: Three-month rate of symptomatic VTE and clinical outcomes after an initially normal single proximal US result. RESULTS: Of 1295 patients, 111 (8.6%) were found to have acute deep venous thrombosis on the initial proximal US. Of the remaining 1184 patients with initially normal results on proximal US who were sampled at 3-month follow-up, 1075 patients (90.8%) had no venous thromboembolic event. Among the others, 11 (0.9%) had a subsequent imaging-confirmed venous thromboembolic event, 53 (4.5%) died (none owing to venous thromboembolism), and 45 (3.8%) did not complete follow-up. CONCLUSION: Symptomatic VTE after an initially normal single proximal US result occurred in less than 1% of this cohort. Therefore, serial proximal US is unnecessary for most of our patients, and its elimination will save time and out-of-pocket expenses.
CONTEXT: The optimal lower extremity venous ultrasound (US) protocol to diagnose deep venous thrombosis of the popliteal and more proximal veins is unclear. OBJECTIVE: To determine the three-month rate of symptomatic venous thromboembolism (VTE) and clinical outcomes of inpatients and ambulatory patients with normal findings on single venous ultrasound of the popliteal and more proximal veins (single proximal US). DESIGN: Single proximal US results and clinical data of all inpatient and ambulatory patients with suspected acute deep venous thrombosis were retrospectively reviewed during a 12-month period between January and December 2014. Three-month follow-up data were reviewed for all these patients, who received all their care from a single geographically isolated health maintenance organization. MAIN OUTCOME MEASURES: Three-month rate of symptomatic VTE and clinical outcomes after an initially normal single proximal US result. RESULTS: Of 1295 patients, 111 (8.6%) were found to have acute deep venous thrombosis on the initial proximal US. Of the remaining 1184 patients with initially normal results on proximal US who were sampled at 3-month follow-up, 1075 patients (90.8%) had no venous thromboembolic event. Among the others, 11 (0.9%) had a subsequent imaging-confirmed venous thromboembolic event, 53 (4.5%) died (none owing to venous thromboembolism), and 45 (3.8%) did not complete follow-up. CONCLUSION: Symptomatic VTE after an initially normal single proximal US result occurred in less than 1% of this cohort. Therefore, serial proximal US is unnecessary for most of our patients, and its elimination will save time and out-of-pocket expenses.
Authors: A Cogo; A W Lensing; M M Koopman; F Piovella; S Siragusa; P S Wells; S Villalta; H R Büller; A G Turpie; P Prandoni Journal: BMJ Date: 1998-01-03
Authors: B G Birdwell; G E Raskob; T L Whitsett; S S Durica; P C Comp; J N George; T L Tytle; P A McKee Journal: Ann Intern Med Date: 1998-01-01 Impact factor: 25.391
Authors: Sebastian M Schellong; Thomas Schwarz; Kai Halbritter; Jan Beyer; Gabriele Siegert; Wolfram Oettler; Benjamin Schmidt; Hans E Schroeder Journal: Thromb Haemost Date: 2003-02 Impact factor: 5.249
Authors: Antoine Elias; Luc Mallard; Marie Elias; Catherine Alquier; François Guidolin; Bruno Gauthier; Alain Viard; Pierre Mahouin; Anne Vinel; Henri Boccalon Journal: Thromb Haemost Date: 2003-02 Impact factor: 5.249
Authors: Scott M Stevens; C Gregory Elliott; Karen J Chan; Marlene J Egger; Kirmanj M Ahmed Journal: Ann Intern Med Date: 2004-06-15 Impact factor: 25.391
Authors: A W Lensing; P Prandoni; D Brandjes; P M Huisman; M Vigo; G Tomasella; J Krekt; J Wouter Ten Cate; M V Huisman; H R Büller Journal: N Engl J Med Date: 1989-02-09 Impact factor: 91.245
Authors: Noémie Kraaijpoel; Marc Carrier; Grégoire Le Gal; Matthew D F McInnes; Jean-Paul Salameh; Trevor A McGrath; Nick van Es; David Moher; Harry R Büller; Patrick M Bossuyt; Mariska M G Leeflang Journal: PLoS One Date: 2020-02-11 Impact factor: 3.240