Literature DB >> 28401190

Multigene profiling of single circulating tumor cells.

Seung-Min Park1, Dawson J Wong2, Chin Chun Ooi3, Jared C Nesvet4, Viswam S Nair5, Shan X Wang6, Sanjiv S Gambhir7.   

Abstract

Numerous techniques for isolating circulating tumor cells (CTCs) have been developed. Concurrently, single-cell techniques that can reveal molecular components of CTCs have become widely available. We discuss how the combination of isolation and multigene profiling of single CTCs in our platform can facilitate eventual translation to the clinic.

Entities:  

Keywords:  Circulating tumor cells; rare-cell sorting; single-cell analysis

Year:  2017        PMID： 28401190      PMCID： PMC5383366          DOI： 10.1080/23723556.2017.1289295

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  7 in total

Review 1.  Toward integrated molecular diagnostic system (i MDx): principles and applications.

Authors:  Seung-Min Park; Andrew F Sabour; Jun Ho Son; Sang Hun Lee; Luke P Lee
Journal:  IEEE Trans Biomed Eng       Date:  2014-05       Impact factor: 4.538

Review 2.  Molecular analysis of circulating tumour cells-biology and biomarkers.

Authors:  Matthew G Krebs; Robert L Metcalf; Louise Carter; Ged Brady; Fiona H Blackhall; Caroline Dive
Journal:  Nat Rev Clin Oncol       Date:  2014-01-21       Impact factor: 66.675

Review 3.  Circulating tumor cells: liquid biopsy of cancer.

Authors:  Catherine Alix-Panabières; Klaus Pantel
Journal:  Clin Chem       Date:  2012-09-26       Impact factor: 8.327

4.  Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips.

Authors:  Christopher M Earhart; Casey E Hughes; Richard S Gaster; Chin Chun Ooi; Robert J Wilson; Lisa Y Zhou; Eric W Humke; Lingyun Xu; Dawson J Wong; Stephen B Willingham; Erich J Schwartz; Irving L Weissman; Stefanie S Jeffrey; Joel W Neal; Rajat Rohatgi; Heather A Wakelee; Shan X Wang
Journal:  Lab Chip       Date:  2014-01-07       Impact factor: 6.799

5.  Dual transcript and protein quantification in a massive single cell array.

Authors:  Seung-Min Park; Jae Young Lee; Soongweon Hong; Sang Hun Lee; Ivan K Dimov; Hojae Lee; Susie Suh; Qiong Pan; Keyu Li; Anna M Wu; Shannon M Mumenthaler; Parag Mallick; Luke P Lee
Journal:  Lab Chip       Date:  2016-08-22       Impact factor: 6.799

6.  Molecular profiling of single circulating tumor cells from lung cancer patients.

Authors:  Seung-Min Park; Dawson J Wong; Chin Chun Ooi; David M Kurtz; Ophir Vermesh; Amin Aalipour; Susie Suh; Kelsey L Pian; Jacob J Chabon; Sang Hun Lee; Mehran Jamali; Carmen Say; Justin N Carter; Luke P Lee; Ware G Kuschner; Erich J Schwartz; Joseph B Shrager; Joel W Neal; Heather A Wakelee; Maximilian Diehn; Viswam S Nair; Shan X Wang; Sanjiv S Gambhir
Journal:  Proc Natl Acad Sci U S A       Date:  2016-12-12       Impact factor: 11.205

7.  Discriminating cellular heterogeneity using microwell-based RNA cytometry.

Authors:  Ivan K Dimov; Rong Lu; Eric P Lee; Jun Seita; Debashis Sahoo; Seung-min Park; Irving L Weissman; Luke P Lee
Journal:  Nat Commun       Date:  2014-03-25       Impact factor: 14.919
  7 in total

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