Literature DB >> 28393023

Mathematical analysis of corneal remodelling after intracorneal ring surgery in keratoconus.

Elias F Jarade1, Elise Slim2, Carole Cherfan3, Hala El Rami4, Toufic Hassan4, Elias Chelala4.   

Abstract

AIM: To represent mathematically the intersection between the ectatic corneal geometry and the plane of intracorneal ring implants (ICRS) in order to determine the corneal response to ICRS surgery in keratoconus (KC). Thereafter, to present the concept and early results of a newly derived topography-guided nomogram for ICRS surgery for the treatment of keratectasia.
METHODS: The corneal rings plane intersection was modelled to a conic section. Ring effect was the result of: the ring size, position (steep vs flat), location (distance from the geometric centre of the cornea), and the discrepancy between the ring's curvature and the tunnel's curvature. Femtosecond laser was used to create the tunnels and the incision sites were chosen according to the nomogram in order to place the thickest ring in the steepest portion of the cornea regardless of the astigmatism axis of refraction.
RESULTS: The conic section had a more prolate shape in the steep area of the cornea than in the flat area, depending on the corneal sagittal curvature. Equal ring size had more flattening effect in the steep area than in the flat area. Thick segment should be implanted under the steep portion of the cornea regardless of the cylinder axis of refraction. Single segment in the steep area was sufficient in early and moderate cases of KC. The new nomogram provided more topographic regularity with significant reduction of astigmatism and better improvement in uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA) than the conventional nomogram.
CONCLUSION: The newly derived nomogram can produce better results than the conventional nomogram. Moreover, based on this concept, a new nomogram can be integrated into the femtosecond laser software to create topography-guided, customized, elliptical tunnels with modified focal asphericity that allows for customized focal flattening of the irregularly steepened ectatic cornea.

Entities:  

Keywords:  cornea; intracorneal ring; keratoconus; mathematical model; nomogram; topography guided

Year:  2017        PMID: 28393023      PMCID: PMC5360767          DOI: 10.18240/ijo.2017.03.04

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


  18 in total

1.  Modeling the intracorneal ring segment effect in keratoconus using refractive, keratometric, and corneal aberrometric data.

Authors:  David P Piñero; Jorge L Alio; Miguel A Teus; Rafael I Barraquer; Antonio Uceda-Montañés
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-05-26       Impact factor: 4.799

2.  A single 210-degree arc length intrastromal corneal ring implantation for the management of pellucid marginal corneal degeneration.

Authors:  Anil Kubaloglu; Esin Sogutlu Sari; Yasin Cinar; Arif Koytak; Ekrem Kurnaz; David P Piñero; Yusuf Ozerturk
Journal:  Am J Ophthalmol       Date:  2010-06-08       Impact factor: 5.258

3.  Keratoconus managed with intacs: one-year results.

Authors:  Samuel Levinger; Russell Pokroy
Journal:  Arch Ophthalmol       Date:  2005-10

4.  One or 2 Intacs segments for the correction of keratoconus.

Authors:  Jorge L Alió; Alberto Artola; Ahmed Hassanein; Hazem Haroun; Ahmed Galal
Journal:  J Cataract Refract Surg       Date:  2005-05       Impact factor: 3.351

5.  First clinical results with the femtosecond neodynium-glass laser in refractive surgery.

Authors:  Imola Ratkay-Traub; Istvan E Ferincz; Tibor Juhasz; Ron M Kurtz; Ronald R Krueger
Journal:  J Refract Surg       Date:  2003 Mar-Apr       Impact factor: 3.573

6.  INTACS inserts using the femtosecond laser compared to the mechanical spreader in the treatment of keratoconus.

Authors:  Yaron S Rabinowitz; Xiaohui Li; Teresa S Ignacio; Ezra Maguen
Journal:  J Refract Surg       Date:  2006-10       Impact factor: 3.573

7.  Treating keratoconus with intacs corneal ring segments.

Authors:  Timo Hellstedt; Janna Mäkelä; Raimo Uusitalo; Sinan Emre; Risto Uusitalo
Journal:  J Refract Surg       Date:  2005 May-Jun       Impact factor: 3.573

8.  Biomechanics of Corneal Ring Implants.

Authors:  Albert Daxer
Journal:  Cornea       Date:  2015-11       Impact factor: 2.651

Review 9.  The use of intracorneal ring segments in keratoconus.

Authors:  Alfredo Vega-Estrada; Jorge L Alio
Journal:  Eye Vis (Lond)       Date:  2016-03-15

10.  Intracorneal asymmetrical rings for keratoconus: where should the thicker segment be implanted?

Authors:  Jorge L Alió; Mohamed H Shabayek
Journal:  J Refract Surg       Date:  2006-03       Impact factor: 3.573

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  5 in total

1.  Management of cataract in keratoconus: early visual outcomes of different treatment modalities.

Authors:  Nicolas Arej; Wassef Chanbour; Karen Zaarour; Mazen Amro; Hala El-Rami; Fadi Harb; Elias Jarade
Journal:  Int J Ophthalmol       Date:  2019-10-18       Impact factor: 1.779

2.  The Effect of Age on Corneal Topographic Indices, Keratometry and Visual Acuity After Combined Intrastromal Corneal Ring Segment (ICRS) Implantation and Corneal Crosslinking.

Authors:  Sylvain El-Khoury; Youssef Abdelmassih; Mazen Amro; Ali Dirani; Carol Cherfan; Elias Jarade
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2020-03-30

3.  The number of intracorneal ring segments in asymmetric and central cones.

Authors:  Canan Asli Utine; Denizcan Özizmirliler; Mustafa Kayabaşı; Üzeyir Günenç
Journal:  Eye Vis (Lond)       Date:  2021-03-30

4.  Corneal Cross-Linking for Keratoconus and Post-LASIK Ectasia and Failure Rate: A 3 Years Follow-Up Study.

Authors:  Wassef Chanbour; Lulwa El Zein; Mohamad Ali Younes; Mohamad Issa; Pramod Warhekar; Elias Chelala; Elias Jarade
Journal:  Cureus       Date:  2021-11-13

5.  Clinical outcomes after intracorneal ring segment implantation for keratoconus management in corneas with mild apical haze.

Authors:  Mohamed Elalfy; Sundas Maqsood; Aja Reinhold; Georgios D Panos; Aye Khine; Damian Lake; Samer Hamada; Zisis Gatzioufas
Journal:  Ther Adv Ophthalmol       Date:  2021-03-24
  5 in total

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