| Literature DB >> 28391621 |
Gururaj Arakeri1, Shekar Gowda Patil2, Abdulsalam S Aljabab3, Kuan-Chou Lin4, M A W Merkx5, Shan Gao6,7, Peter A Brennan8.
Abstract
Oral submucous fibrosis (OSMF) is a potentially malignant condition associated with areca nut chewing. Formerly confined to the Indian subcontinent, it is now often seen in Asian populations of the United Kingdom, USA and other developed countries, and is therefore a serious problem for global health. What makes it more sinister is the malignant transformation rate, which has been reported to be around 7.6% over a 17-year period. In this concise article, we review the current trends in the pathophysiology of malignant transformation of OSMF.Entities:
Keywords: malignant transformation; oral submucous fibrosis; review; squamous cell carcinoma
Mesh:
Year: 2017 PMID: 28391621 DOI: 10.1111/jop.12582
Source DB: PubMed Journal: J Oral Pathol Med ISSN: 0904-2512 Impact factor: 4.253