Literature DB >> 2838957

Molecular cloning and nucleotide sequence of the pestivirus bovine viral diarrhea virus.

M S Colett1, R Larson, C Gold, D Strick, D K Anderson, A F Purchio.   

Abstract

The RNA genome of the cytopathic NADL isolate of bovine viral diarrhea virus (BVDV) has been molecularly cloned and the nucleotide sequence determined. The cloned sequence was 12,573 nucleotides in length, corresponding to a molecular weight of 4.3 X 10(6), having a base composition of 32.2% A, 25.7% G, 22.1% U, and 20.0% C. However, the sequences at the 5' and 3' termini of the RNA have not been unequivocally established. A single major open reading frame extending the length of the molecule was found in the viral-sense (positive polarity) sequence. This open reading frame was capable of encoding 3988 amino acids, representing 449 kDa of protein.

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Year:  1988        PMID： 2838957     DOI： 10.1016/0042-6822(88)90672-1

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  133 in total

1.  Mutations in the 5' nontranslated region of bovine viral diarrhea virus result in altered growth characteristics.

Authors:  P Becher; M Orlich; H J Thiel
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

2.  A cellular J-domain protein modulates polyprotein processing and cytopathogenicity of a pestivirus.

Authors:  G Rinck; C Birghan; T Harada; G Meyers; H J Thiel; N Tautz
Journal:  J Virol       Date:  2001-10       Impact factor: 5.103

3.  CRISPR/Cas9-Mediated Knockout of DNAJC14 Verifies This Chaperone as a Pivotal Host Factor for RNA Replication of Pestiviruses.

Authors:  O Isken; A Postel; B Bruhn; E Lattwein; P Becher; N Tautz
Journal:  J Virol       Date:  2019-02-19       Impact factor: 5.103

4.  Deletions of structural glycoprotein E2 of classical swine fever virus strain alfort/187 resolve a linear epitope of monoclonal antibody WH303 and the minimal N-terminal domain essential for binding immunoglobulin G antibodies of a pig hyperimmune serum.

Authors:  M Lin; F Lin; M Mallory; A Clavijo
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

5.  A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases.

Authors:  Jeremy A Bruenn
Journal:  Nucleic Acids Res       Date:  2003-04-01       Impact factor: 16.971

6.  A structural model of pestivirus E(rns) based on disulfide bond connectivity and homology modeling reveals an extremely rare vicinal disulfide.

Authors:  J P M Langedijk; P A van Veelen; W M M Schaaper; A H de Ru; R H Meloen; M M Hulst
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

7.  Viral sequence insertions and a novel cellular insertion in the NS2 gene of cytopathic isolates of bovine viral diarrhea virus as potential cytopathogenicity markers.

Authors:  Adám Bálint; Vilmos Pálfi; Sándor Belák; Claudia Baule
Journal:  Virus Genes       Date:  2005-01       Impact factor: 2.332

8.  Cell-derived sequences in the N-terminal region of the polyprotein of a cytopathogenic pestivirus.

Authors:  A Müller; G Rinck; H-J Thiel; N Tautz
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

9.  Isolation and characterization of noncytopathic pestivirus mutants reveals a role for nonstructural protein NS4B in viral cytopathogenicity.

Authors:  L Qu; L K McMullan; C M Rice
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

10.  Pestiviruses isolated from pigs, cattle and sheep can be allocated into at least three genogroups using polymerase chain reaction and restriction endonuclease analysis.

Authors:  S Vilcek; A J Herring; J A Herring; P F Nettleton; J P Lowings; D J Paton
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574
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