Literature DB >> 28388612

The Drug Repurposing Hub: a next-generation drug library and information resource.

Steven M Corsello1,2,3, Joshua A Bittker1, Zihan Liu1, Joshua Gould1, Patrick McCarren1, Jodi E Hirschman1, Stephen E Johnston1, Anita Vrcic1, Bang Wong1, Mariya Khan1, Jacob Asiedu1, Rajiv Narayan1, Christopher C Mader1, Aravind Subramanian1, Todd R Golub1,3,4,5.   

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Year:  2017        PMID： 28388612      PMCID： PMC5568558          DOI： 10.1038/nm.4306

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  13 in total

1.  Stability through the ages: the GSK experience.

Authors:  Zoe Blaxill; Sue Holland-Crimmin; Rob Lifely
Journal:  J Biomol Screen       Date:  2009-05-21

2.  Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group.

Authors:  I Goldstein; T F Lue; H Padma-Nathan; R C Rosen; W D Steers; P A Wicker
Journal:  N Engl J Med       Date:  1998-05-14       Impact factor: 91.245

3.  Clinical development success rates for investigational drugs.

Authors:  Michael Hay; David W Thomas; John L Craighead; Celia Economides; Jesse Rosenthal
Journal:  Nat Biotechnol       Date:  2014-01       Impact factor: 54.908

4.  Can you teach old drugs new tricks?

Authors:  Nicola Nosengo
Journal:  Nature       Date:  2016-06-16       Impact factor: 49.962

5.  The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics.

Authors:  Ruili Huang; Noel Southall; Yuhong Wang; Adam Yasgar; Paul Shinn; Ajit Jadhav; Dac-Trung Nguyen; Christopher P Austin
Journal:  Sci Transl Med       Date:  2011-04-27       Impact factor: 17.956

Review 6.  Thalidomide for treatment of multiple myeloma: 10 years later.

Authors:  Antonio Palumbo; Thierry Facon; Pieter Sonneveld; Joan Bladè; Massimo Offidani; Francesca Gay; Philippe Moreau; Anders Waage; Andrew Spencer; Heinz Ludwig; Mario Boccadoro; Jean-Luc Harousseau
Journal:  Blood       Date:  2008-02-01       Impact factor: 22.113

7.  InChI, the IUPAC International Chemical Identifier.

Authors:  Stephen R Heller; Alan McNaught; Igor Pletnev; Stephen Stein; Dmitrii Tchekhovskoi
Journal:  J Cheminform       Date:  2015-05-30       Impact factor: 5.514

8.  Discovery and saturation analysis of cancer genes across 21 tumour types.

Authors:  Michael S Lawrence; Petar Stojanov; Craig H Mermel; James T Robinson; Levi A Garraway; Todd R Golub; Matthew Meyerson; Stacey B Gabriel; Eric S Lander; Gad Getz
Journal:  Nature       Date:  2014-01-05       Impact factor: 49.962

9.  High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines.

Authors:  Channing Yu; Aristotle M Mannan; Griselda Metta Yvone; Kenneth N Ross; Yan-Ling Zhang; Melissa A Marton; Bradley R Taylor; Andrew Crenshaw; Joshua Z Gould; Pablo Tamayo; Barbara A Weir; Aviad Tsherniak; Bang Wong; Levi A Garraway; Alykhan F Shamji; Michelle A Palmer; Michael A Foley; Wendy Winckler; Stuart L Schreiber; Andrew L Kung; Todd R Golub
Journal:  Nat Biotechnol       Date:  2016-02-29       Impact factor: 54.908

10.  Therapeutic target database update 2014: a resource for targeted therapeutics.

Authors:  Chu Qin; Cheng Zhang; Feng Zhu; Feng Xu; Shang Ying Chen; Peng Zhang; Ying Hong Li; Sheng Yong Yang; Yu Quan Wei; Lin Tao; Yu Zong Chen
Journal:  Nucleic Acids Res       Date:  2013-11-21       Impact factor: 16.971
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  202 in total

1.  OCTAD: an open workspace for virtually screening therapeutics targeting precise cancer patient groups using gene expression features.

Authors:  Billy Zeng; Benjamin S Glicksberg; Patrick Newbury; Evgeny Chekalin; Jing Xing; Ke Liu; Anita Wen; Caven Chow; Bin Chen
Journal:  Nat Protoc       Date:  2020-12-23       Impact factor: 13.491

Review 2.  The multitargeted drug ivermectin: from an antiparasitic agent to a repositioned cancer drug.

Authors:  Mandy Juarez; Alejandro Schcolnik-Cabrera; Alfonso Dueñas-Gonzalez
Journal:  Am J Cancer Res       Date:  2018-02-01       Impact factor: 6.166

3.  The Effects of Morphine, Baclofen, and Buspirone Alone and in Combination on Schedule-Controlled Responding and Hot Plate Antinociception in Rats.

Authors:  Jenny L Wilkerson; Jasmine S Felix; Luis F Restrepo; Mohd Imran Ansari; Andrew Coop; Lance R McMahon
Journal:  J Pharmacol Exp Ther       Date:  2019-06-24       Impact factor: 4.030

Review 4.  Screening Repurposing Libraries for Identification of Drugs with Novel Antifungal Activity.

Authors:  Gina Wall; Jose L Lopez-Ribot
Journal:  Antimicrob Agents Chemother       Date:  2020-08-20       Impact factor: 5.191

5.  Combinatorial drug discovery in nanoliter droplets.

Authors:  Anthony Kulesa; Jared Kehe; Juan E Hurtado; Prianca Tawde; Paul C Blainey
Journal:  Proc Natl Acad Sci U S A       Date:  2018-06-13       Impact factor: 11.205

6.  Workflow for defining reference chemicals for assessing performance of in vitro assays.

Authors:  Richard S Judson; Russell S Thomas; Nancy Baker; Anita Simha; Xia Meng Howey; Carmen Marable; Nicole C Kleinstreuer; Keith A Houck
Journal:  ALTEX       Date:  2018-12-17       Impact factor: 6.043

7.  Competitive Kinase Enrichment Proteomics Reveals that Abemaciclib Inhibits GSK3β and Activates WNT Signaling.

Authors:  Emily M Cousins; Dennis Goldfarb; Feng Yan; Jose Roques; David Darr; Gary L Johnson; Michael B Major
Journal:  Mol Cancer Res       Date:  2017-11-13       Impact factor: 5.852

Review 8.  Drug Repurposing in Parkinson's Disease.

Authors:  Dilan Athauda; Thomas Foltynie
Journal:  CNS Drugs       Date:  2018-08       Impact factor: 5.749

Review 9.  From gene networks to drugs: systems pharmacology approaches for AUD.

Authors:  Laura B Ferguson; R Adron Harris; Roy Dayne Mayfield
Journal:  Psychopharmacology (Berl)       Date:  2018-03-01       Impact factor: 4.530

10.  Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells.

Authors:  Filip Roudnicky; Jitao David Zhang; Bo Kyoung Kim; Nikhil J Pandya; Yanjun Lan; Lisa Sach-Peltason; Heloise Ragelle; Pamela Strassburger; Sabine Gruener; Mirjana Lazendic; Sabine Uhles; Franco Revelant; Oliv Eidam; Gregor Sturm; Verena Kueppers; Klaus Christensen; Leonard D Goldstein; Manuel Tzouros; Balazs Banfai; Zora Modrusan; Martin Graf; Christoph Patsch; Mark Burcin; Claas A Meyer; Peter D Westenskow; Chad A Cowan
Journal:  Proc Natl Acad Sci U S A       Date:  2020-08-05       Impact factor: 11.205
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