Literature DB >> 28388461

Activation-induced deoxycytidine deaminase: Structural basis for favoring WRC hot motif specificities unique among APOBEC family members.

Phuong Pham1, Samir A Afif1, Mayuko Shimoda2, Kazuhiko Maeda3, Nobuo Sakaguchi4, Lars C Pedersen5, Myron F Goodman6.   

Abstract

Entities:  

Keywords:  AID X-ray crystal structure; Antibody diversity; C-deamination motif selectivity; IgV somatic hypermutation

Mesh：

Substances：

Year:  2017        PMID： 28388461      PMCID： PMC6408873          DOI： 10.1016/j.dnarep.2017.03.007

Source DB:  PubMed          Journal:  DNA Repair (Amst)        ISSN： 1568-7856


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  19 in total

1.  C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

Authors:  Vasco Barreto; Bernardo Reina-San-Martin; Almudena R Ramiro; Kevin M McBride; Michel C Nussenzweig
Journal:  Mol Cell       Date:  2003-08       Impact factor: 17.970

2.  Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo.

Authors:  Rupert C L Beale; Svend K Petersen-Mahrt; Ian N Watt; Reuben S Harris; Cristina Rada; Michael S Neuberger
Journal:  J Mol Biol       Date:  2004-03-26       Impact factor: 5.469

3.  A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase.

Authors:  Rahul M Kohli; Shaun R Abrams; Kiran S Gajula; Robert W Maul; Patricia J Gearhart; James T Stivers
Journal:  J Biol Chem       Date:  2009-06-26       Impact factor: 5.157

4.  Analysis of a single-stranded DNA-scanning process in which activation-induced deoxycytidine deaminase (AID) deaminates C to U haphazardly and inefficiently to ensure mutational diversity.

Authors:  Phuong Pham; Peter Calabrese; Soo Jung Park; Myron F Goodman
Journal:  J Biol Chem       Date:  2011-05-12       Impact factor: 5.157

5.  Determinants of sequence-specificity within human AID and APOBEC3G.

Authors:  Michael A Carpenter; Erandi Rajagurubandara; Priyanga Wijesinghe; Ashok S Bhagwat
Journal:  DNA Repair (Amst)       Date:  2010-03-24

6.  V-region mutation in vitro, in vivo, and in silico reveal the importance of the enzymatic properties of AID and the sequence environment.

Authors:  Thomas MacCarthy; Susan L Kalis; Sergio Roa; Phuong Pham; Myron F Goodman; Matthew D Scharff; Aviv Bergman
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-14       Impact factor: 11.205

7.  AID mutant analyses indicate requirement for class-switch-specific cofactors.

Authors:  Van-Thanh Ta; Hitoshi Nagaoka; Nadia Catalan; Anne Durandy; Alain Fischer; Kohsuke Imai; Shigeaki Nonoyama; Junko Tashiro; Masaya Ikegawa; Satomi Ito; Kazuo Kinoshita; Masamichi Muramatsu; Tasuku Honjo
Journal:  Nat Immunol       Date:  2003-08-10       Impact factor: 25.606

8.  Separate domains of AID are required for somatic hypermutation and class-switch recombination.

Authors:  Reiko Shinkura; Satomi Ito; Nasim A Begum; Hitoshi Nagaoka; Masamichi Muramatsu; Kazuo Kinoshita; Yoshimasa Sakakibara; Hiroko Hijikata; Tasuku Honjo
Journal:  Nat Immunol       Date:  2004-06-13       Impact factor: 25.606

9.  Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation.

Authors:  Phuong Pham; Ronda Bransteitter; John Petruska; Myron F Goodman
Journal:  Nature       Date:  2003-06-18       Impact factor: 49.962

10.  Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID.

Authors:  Meng Wang; Cristina Rada; Michael S Neuberger
Journal:  J Exp Med       Date:  2010-01-04       Impact factor: 14.307
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  6 in total

1.  Efficient CRISPR-mediated base editing in Agrobacterium spp.

Authors:  Savio D Rodrigues; Mansour Karimi; Lennert Impens; Els Van Lerberge; Griet Coussens; Stijn Aesaert; Debbie Rombaut; Dominique Holtappels; Heba M M Ibrahim; Marc Van Montagu; Jeroen Wagemans; Thomas B Jacobs; Barbara De Coninck; Laurens Pauwels
Journal:  Proc Natl Acad Sci U S A       Date:  2020-12-21       Impact factor: 11.205

Review 2.  Current insights into the mechanism of mammalian immunoglobulin class switch recombination.

Authors:  Kefei Yu; Michael R Lieber
Journal:  Crit Rev Biochem Mol Biol       Date:  2019-09-11       Impact factor: 8.250

3.  The role of HIRA-dependent H3.3 deposition and its modifications in the somatic hypermutation of immunoglobulin variable regions.

Authors:  Guojun Yu; Yongwei Zhang; Varun Gupta; Jinghang Zhang; Thomas MacCarthy; Zhi Duan; Matthew D Scharff
Journal:  Proc Natl Acad Sci U S A       Date:  2021-12-14       Impact factor: 12.779

4.  Hydrogen bonds are a primary driving force for de novo protein folding.

Authors:  Schuyler Lee; Chao Wang; Haolin Liu; Jian Xiong; Renee Jiji; Xia Hong; Xiaoxue Yan; Zhangguo Chen; Michal Hammel; Yang Wang; Shaodong Dai; Jing Wang; Chengyu Jiang; Gongyi Zhang
Journal:  Acta Crystallogr D Struct Biol       Date:  2017-11-10       Impact factor: 7.652

5.  A fluorescent reporter for quantification and enrichment of DNA editing by APOBEC-Cas9 or cleavage by Cas9 in living cells.

Authors:  Amber St Martin; Daniel Salamango; Artur Serebrenik; Nadine Shaban; William L Brown; Francesco Donati; Uday Munagala; Silvestro G Conticello; Reuben S Harris
Journal:  Nucleic Acids Res       Date:  2018-08-21       Impact factor: 16.971

6.  AID assists DNMT1 to attenuate BCL6 expression through DNA methylation in diffuse large B-cell lymphoma cell lines.

Authors:  Junna Jiao; Zhuangwei Lv; Ping Zhang; Yang Wang; Meng Yuan; Xiaozhuo Yu; Woodvine Otieno Odhiambo; Mingzhe Zheng; Hua Zhang; Yunfeng Ma; Yanhong Ji
Journal:  Neoplasia       Date:  2020-02-12       Impact factor: 5.715
  6 in total

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