Literature DB >> 2838772

Clinical evaluation of tumour imaging using 99Tc(V)m dimercaptosuccinic acid, a new tumour-seeking agent.

H Ohta1, K Endo, T Fujita, J Konishi, K Torizuka, K Horiuchi, A Yokoyama.   

Abstract

Considering the favourable nuclear properties of 99Tcm over 67Ga, we have developed a new tumour-seeking agent, 99Tc(V)m dimercaptosuccinic acid (Tc(V)-DMSA). In order to evaluate the clinical usefulness of Tc(V)-DMSA scintigraphies, 492 patients were studied with Tc(V)-DMSA, and in some cases, where possible, the results were compared with conventional 67Ga citrate scintigraphies. There was a high degree of usefulness of Tc(V)-DMSA in patients with head and neck tumours, medullary thyroid carcinomas and soft tissue tumours. But in patients with carcinomas of the lung, liver and gastrointestinal tract, malignant melanoma and lymphoma, Tc(V)-DMSA was of no or little use.

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Year:  1988        PMID： 2838772

Source DB:  PubMed          Journal:  Nucl Med Commun        ISSN： 0143-3636            Impact factor:   1.690


  19 in total

1.  Pentavalent technetium-99m dimercaptosuccinic acid scintigraphy is useful in diagnosis and localization of neuroblastoma.

Authors:  C S Bal; V Raina; A K Padhy; P K Pradhan; C Sarkar
Journal:  Postgrad Med J       Date:  1992-09       Impact factor: 2.401

2.  Positive imaging of cardiomyopathy with 99mTc(V)-DMSA.

Authors:  H Ohta; T Komibuchi; S Kawamata; K Yamamoto; M Shichirousako; T Wada; H Kotoura; K Shizuki; K Endo; J Konishi
Journal:  Ann Nucl Med       Date:  1992-11       Impact factor: 2.668

3.  Comparison of the efficacy of clinical examination, ultrasound neck and computed tomography in detection and staging of cervical lymph node metastasis in head and neck cancers.

Authors:  Nitin Anand; Neena Chaudhary; M K Mittal; Rajni Prasad
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2007-04-26

4.  In vitro and in vivo studies with pentavalent technetium-99m dimercaptosuccinic acid.

Authors:  A S Lam; M R Puncher; P J Blower
Journal:  Eur J Nucl Med       Date:  1996-12

5.  Using technetium-99m (V) dimercaptosuccinic acid to detect malignancies from single solid masses in the lungs.

Authors:  C H Kao; S J Wang; S P Wey; L H Shen; G Ting; S H Yeh
Journal:  Eur J Nucl Med       Date:  1992

6.  Preparation and clinical evaluation of technetium-99m dimercaptosuccinic acid for tumour scintigraphy.

Authors:  T Hirano; K Tomiyoshi; Y J Zhang; T Ishida; T Inoue; K Endo
Journal:  Eur J Nucl Med       Date:  1994-01

7.  In vitro and in vivo evaluation of the influence of type III NaPi co-transporter activity during apoptosis on 99mTc-(V)DMSA uptake in the human leukaemic cell line U937.

Authors:  Delphine Denoyer; Nathalie Perek; Nathalie Le Jeune; Delphine Frere; Odile Sabido; Anthony Clotagatide; Francis Dubois
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-06-16       Impact factor: 9.236

8.  Solitary muscular sarcoidosis: CT, MRI, and scintigraphic characteristics.

Authors:  H Kobayashi; Y Kotoura; H Sakahara; T Yamamuro; K Endo; J Konishi
Journal:  Skeletal Radiol       Date:  1994-05       Impact factor: 2.199

9.  99mTc(V)-DMSA and 99mTc-MDP uptake and no 67Ga-citrate uptake in a case of primary pulmonary leiomyosarcoma.

Authors:  H Ohta; T Komibuchi; H Nishiyama; K Shizuki; Y Miyaki
Journal:  Ann Nucl Med       Date:  1992-08       Impact factor: 2.668

10.  Pitfalls in scintigraphic detection of neuroendocrine tumours.

Authors:  L Feggi; E Degli Uberti; G C Pansini; G Transforini; N Prandini; M R Ambrosio; A R D'Urso; R Faggioli
Journal:  Eur J Nucl Med       Date:  1992
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