Jessica A Zerillo1, Maartje G Schouwenburg2, Annelotte C M van Bommel2, Caleb Stowell3, Jacob Lippa3, Donna Bauer4, Ann M Berger5, Gilles Boland6, Josep M Borras7, Mary K Buss8, Robert Cima9, Eric Van Cutsem10, Eino B van Duyn11, Samuel R G Finlayson12, Skye Hung-Chun Cheng13, Corinna Langelotz14, John Lloyd15, Andrew C Lynch16, Harvey J Mamon17, Pamela K McAllister18, Bruce D Minsky19, Joanne Ngeow20, Muhammad R Abu Hassan21, Kim Ryan22, Veena Shankaran23, Melissa P Upton24, John Zalcberg25, Cornelis J van de Velde26, Rob Tollenaar26. 1. International Consortium for Health Outcomes Measurement (ICHOM), Cambridge, Massachusetts2Department of Quality and Patient Safety, Dana-Farber Cancer Institute, Boston, Massachusetts3Division of Hematology and Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts. 2. International Consortium for Health Outcomes Measurement (ICHOM), Cambridge, Massachusetts4Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands. 3. International Consortium for Health Outcomes Measurement (ICHOM), Cambridge, Massachusetts. 4. Bowel Cancer Australia, North Sydney, Australia. 5. College of Nursing, University of Nebraska Medical Center, Omaha. 6. Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston. 7. Department of Clinical Sciences, Institut d'Investigació Biomèdica de Bellvitge, University of Barcelona, Barcelona, Spain. 8. Division of Hematology and Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts. 9. Department of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota. 10. Department of Digestive Oncology, University Hospitals Leuven and Katholieke Universiteit Leuven, Leuven, Belgium. 11. Department of Surgery, Medisch Spectrum Twente, Enschede, the Netherlands. 12. Department of Surgery, University of Utah School of Medicine, Salt Lake City. 13. Department of Radiation Oncology, Koo Foundation Sun Yan-Sen Cancer Center, Taiwan. 14. Department of Surgery, Campus Charité Mitte/Campus Virchow, Universitätsmedizin Berlin, Berlin, Germany. 15. Colon Cancer Alliance, Washington, DC. 16. Department of Surgery, Peter MacCallum Cancer Center, East Melbourne, Australia. 17. Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. 18. Fight Colorectal Cancer, Alexandria, Virginia. 19. Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston. 20. Division of Medical Oncology, National Cancer Centre, Singapore. 21. Department of Gastroenterology, Hospital Sultanah Bahiyah, Kedah, Malaysia. 22. Cancer Support Community, Washington, DC. 23. Division of Medical Oncology, Department of Medicine, University of Washington, Seattle. 24. Department of Pathology, University of Washington, Seattle. 25. School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia. 26. Department of Surgery, Leiden University Medical Center, Leiden, the Netherlands.
Abstract
IMPORTANCE: Global health systems are shifting toward value-based care in an effort to drive better outcomes in the setting of rising health care costs. This shift requires a common definition of value, starting with the outcomes that matter most to patients. OBJECTIVE: The International Consortium for Health Outcomes Measurement (ICHOM), a nonprofit initiative, was formed to define standard sets of outcomes by medical condition. In this article, we report the efforts of ICHOM's working group in colorectal cancer. EVIDENCE REVIEW: The working group was composed of multidisciplinary oncology specialists in medicine, surgery, radiation therapy, palliative care, nursing, and pathology, along with patient representatives. Through a modified Delphi process during 8 months (July 8, 2015 to February 29, 2016), ICHOM led the working group to a consensus on a final recommended standard set. The process was supported by a systematic PubMed literature review (1042 randomized clinical trials and guidelines from June 3, 2005, to June 3, 2015), a patient focus group (11 patients with early and metastatic colorectal cancer convened during a teleconference in August 2015), and a patient validation survey (among 276 patients with and survivors of colorectal cancer between October 15, 2015, and November 4, 2015). FINDINGS: After consolidating findings of the literature review and focus group meeting, a list of 40 outcomes was presented to the WG and underwent voting. The final recommendation includes outcomes in the following categories: survival and disease control, disutility of care, degree of health, and quality of death. Selected case-mix factors were recommended to be collected at baseline to facilitate comparison of results across treatments and health care professionals. CONCLUSIONS: A standardized set of patient-centered outcome measures to inform value-based health care in colorectal cancer was developed. Pilot efforts are under way to measure the standard set among members of the working group.
IMPORTANCE: Global health systems are shifting toward value-based care in an effort to drive better outcomes in the setting of rising health care costs. This shift requires a common definition of value, starting with the outcomes that matter most to patients. OBJECTIVE: The International Consortium for Health Outcomes Measurement (ICHOM), a nonprofit initiative, was formed to define standard sets of outcomes by medical condition. In this article, we report the efforts of ICHOM's working group in colorectal cancer. EVIDENCE REVIEW: The working group was composed of multidisciplinary oncology specialists in medicine, surgery, radiation therapy, palliative care, nursing, and pathology, along with patient representatives. Through a modified Delphi process during 8 months (July 8, 2015 to February 29, 2016), ICHOM led the working group to a consensus on a final recommended standard set. The process was supported by a systematic PubMed literature review (1042 randomized clinical trials and guidelines from June 3, 2005, to June 3, 2015), a patient focus group (11 patients with early and metastatic colorectal cancer convened during a teleconference in August 2015), and a patient validation survey (among 276 patients with and survivors of colorectal cancer between October 15, 2015, and November 4, 2015). FINDINGS: After consolidating findings of the literature review and focus group meeting, a list of 40 outcomes was presented to the WG and underwent voting. The final recommendation includes outcomes in the following categories: survival and disease control, disutility of care, degree of health, and quality of death. Selected case-mix factors were recommended to be collected at baseline to facilitate comparison of results across treatments and health care professionals. CONCLUSIONS: A standardized set of patient-centered outcome measures to inform value-based health care in colorectal cancer was developed. Pilot efforts are under way to measure the standard set among members of the working group.
Authors: Larissa Nekhlyudov; Michelle A Mollica; Paul B Jacobsen; Deborah K Mayer; Lawrence N Shulman; Ann M Geiger Journal: J Natl Cancer Inst Date: 2019-11-01 Impact factor: 13.506
Authors: Olga Husson; Bryce B Reeve; Anne-Sophie Darlington; Christabel K Cheung; Samantha Sodergren; Winette T A van der Graaf; John M Salsman Journal: J Natl Cancer Inst Date: 2022-04-11 Impact factor: 13.506
Authors: Mauro Podda; Patricia Sylla; Gianluca Baiocchi; Michel Adamina; Vanni Agnoletti; Ferdinando Agresta; Luca Ansaloni; Alberto Arezzo; Nicola Avenia; Walter Biffl; Antonio Biondi; Simona Bui; Fabio C Campanile; Paolo Carcoforo; Claudia Commisso; Antonio Crucitti; Nicola De'Angelis; Gian Luigi De'Angelis; Massimo De Filippo; Belinda De Simone; Salomone Di Saverio; Giorgio Ercolani; Gustavo P Fraga; Francesco Gabrielli; Federica Gaiani; Mario Guerrieri; Angelo Guttadauro; Yoram Kluger; Ari K Leppaniemi; Andrea Loffredo; Tiziana Meschi; Ernest E Moore; Monica Ortenzi; Francesco Pata; Dario Parini; Adolfo Pisanu; Gilberto Poggioli; Andrea Polistena; Alessandro Puzziello; Fabio Rondelli; Massimo Sartelli; Neil Smart; Michael E Sugrue; Patricia Tejedor; Marco Vacante; Federico Coccolini; Justin Davies; Fausto Catena Journal: World J Emerg Surg Date: 2021-07-02 Impact factor: 5.469
Authors: Daniel P Butler; Alethse De la Torre; Gregory H Borschel; Tessa A Hadlock; Carien Beurskens; Kathleen Bogart; Alexander Cárdenas Mejía; Christopher Coombs; Jocelyne Copeland; Jacqueline Diels; Teresa González-Otero; Louise Graham; Lisa Ishii; Raman Malhotra; Adelaida Martinez; Lisa McKinley; Mara W Robinson; Sinikka Suominen; Akihiko Takushima; Evangelina Vazquez Curiel; Faye L Wachs; Adriaan O Grobbelaar Journal: JAMA Facial Plast Surg Date: 2019-09-01 Impact factor: 4.611
Authors: Pedro Machado; Miguel Morgado; João Raposo; Marco Mendes; Cândida G Silva; Nuno Morais Journal: Support Care Cancer Date: 2022-02-02 Impact factor: 3.603
Authors: Jaheeda Gangannagaripalli; Andrea Albagli; Stacie N Myers; Sarah Whittaker; Andria Joseph; Anna Clarke; Lucy Matkin; Jordi Alonso; Ira Byock; Michael van den Berg; Carolyn Canfield; John Chaplin; Juan Dapueto; Marcelo Pio de Almedia Fleck; Chris Sidey-Gibbons; Jan Hazelzet; Rachel Hess; Kaisa Immonen; Serena Joyner; Catherine Katz; Carolyn Kerrigan; Cindy Lam; Joanne Lunn; Fiona McKenzie; Alastair Roeves; Caleb Stowell; Timothy Switaj; Melissa Tinsley; Eyal Zimlichman; Jose M Valderas Journal: Patient Date: 2021-11-01 Impact factor: 3.481
Authors: M G Torras; E Canals; D Jurado-Bruggeman; S Marín-Borras; M Macià; J Jové; A M Boladeras; C Muñoz-Montplet; J Molero; C Picón; M Puigdemont; L Aliste; A Torrents; F Guedea; J M Borras Journal: Transl Oncol Date: 2018-04-26 Impact factor: 4.243
Authors: Robert P Takes; Gyorgy B Halmos; John A Ridge; Paolo Bossi; Matthias A W Merkx; Alessandra Rinaldo; Alvaro Sanabria; Ludi E Smeele; Antti A Mäkitie; Alfio Ferlito Journal: Curr Oncol Rep Date: 2020-07-10 Impact factor: 5.075