Literature DB >> 2838290

Brain metastases from small cell lung cancer treated with combination chemotherapy.

P E Kristjansen1, H H Hansen.   

Abstract

Ten patients with metastatic small cell lung cancer (SCLC) in the brain, shown by CT scan at time of diagnosis, were treated with systemic combination chemotherapy. Repeated CT scans were performed every 4 weeks. Seven patients were evaluable, since three patients died during the first 2-3 weeks. Significant responses on CT scans as well as neurologic improvement were demonstrated in all evaluable patients. Four of seven patients obtained a complete response in the brain, while three had partial remissions. The impact of this observation on the overall treatment strategies in SCLC has further to be defined.

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Mesh：

Year:  1988        PMID： 2838290     DOI： 10.1016/s0277-5379(98)90035-9

Source DB:  PubMed          Journal:  Eur J Cancer Clin Oncol        ISSN： 0277-5379


  9 in total

Review 1.  The impact of surgery on the multidisciplinary treatment of bronchogenic small cell carcinoma (updated review including ongoing studies).

Authors:  W Theuer; O Selawry; K Karrer
Journal:  Med Oncol Tumor Pharmacother       Date:  1992

2.  Chemotherapy by fotemustine in cerebral metastases of disseminated malignant melanoma.

Authors:  C Jacquillat; D Khayat; P Banzet; M Weil; M F Avril; P Fumoleau; M Namer; J Bonneterre; P Kerbrat; J J Bonerandi
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

3.  A comparative study of vascular proliferation in brain metastasis of lung carcinomas.

Authors:  T Ito; H Kitamura; N Nakamura; Y Kameda; M Kanisawa
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1993

Review 4.  Management of metastatic brain tumors.

Authors:  R Sawaya; B L Ligon; R K Bindal
Journal:  Ann Surg Oncol       Date:  1994-03       Impact factor: 5.344

5.  Brain metastases in breast cancer; natural history, prognostic factors and outcome.

Authors:  W Boogerd; V W Vos; A A Hart; G Baris
Journal:  J Neurooncol       Date:  1993-02       Impact factor: 4.130

6.  High dose etoposide for brain metastases of small cell lung cancer. A phase II study. The EORTC Lung Cancer Cooperative Group.

Authors:  P E Postmus; H Haaxma-Reiche; D T Sleijfer; A Kirkpatrick; J G McVie; J P Kleisbauer
Journal:  Br J Cancer       Date:  1989-02       Impact factor: 7.640

7.  The response of cerebral metastases in small cell lung cancer to systemic chemotherapy.

Authors:  C J Twelves; R L Souhami; P G Harper; C M Ash; S G Spiro; H M Earl; J S Tobias; H Quinn; D M Geddes
Journal:  Br J Cancer       Date:  1990-01       Impact factor: 7.640

8.  The value of computed tomographic (CT) scan surveillance in the detection and management of brain metastases in patients with small cell lung cancer.

Authors:  J Hardy; I Smith; G Cherryman; M Vincent; I Judson; T Perren; M Williams
Journal:  Br J Cancer       Date:  1990-10       Impact factor: 7.640

9.  A pilot study of concurrent whole-brain radiotherapy and chemotherapy combined with cisplatin, vindesine and mitomycin in non-small-cell lung cancer with brain metastasis.

Authors:  K Furuse; T Kamimori; M Kawahara; N Kodama; M Ogawara; S Atagi; N Naka; M Akira; K Kubota
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640
  9 in total

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