Literature DB >> 28374337

Rescuing Canavan disease: engineering the wrong cell at the right time.

Morris H Baslow1.   

Abstract

Entities:  

Keywords:  ASPA Gene; Aspartoacylase; Canavan Disease; Myelin Layer; Turn Signal

Mesh：

Substances：

Year:  2017        PMID： 28374337     DOI： 10.1007/s10545-017-0038-2

Source DB:  PubMed          Journal:  J Inherit Metab Dis        ISSN： 0141-8955            Impact factor:   4.982


× No keyword cloud information.
  6 in total

1.  Redirecting N-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan disease.

Authors:  Dominic J Gessler; Danning Li; Hongxia Xu; Qin Su; Julio Sanmiguel; Serafettin Tuncer; Constance Moore; Jean King; Reuben Matalon; Guangping Gao
Journal:  JCI Insight       Date:  2017-02-09

2.  Absence of N-acetylaspartate in the human brain: impact on neurospectroscopy?

Authors:  E Martin; A Capone; J Schneider; J Hennig; T Thiel
Journal:  Ann Neurol       Date:  2001-04       Impact factor: 10.422

Review 3.  Functions of N-acetyl-L-aspartate and N-acetyl-L-aspartylglutamate in the vertebrate brain: role in glial cell-specific signaling.

Authors:  M H Baslow
Journal:  J Neurochem       Date:  2000-08       Impact factor: 5.372

4.  Expression of aspartoacylase activity in cultured rat macroglial cells is limited to oligodendrocytes.

Authors:  M H Baslow; R F Suckow; V Sapirstein; B L Hungund
Journal:  J Mol Neurosci       Date:  1999 Aug-Oct       Impact factor: 3.444

5.  Are astrocytes the missing link between lack of brain aspartoacylase activity and the spongiform leukodystrophy in Canavan disease?

Authors:  Morris H Baslow; David N Guilfoyle
Journal:  Neurochem Res       Date:  2009-03-25       Impact factor: 3.996

6.  Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia.

Authors:  Elsa Wiame; Donatienne Tyteca; Nathalie Pierrot; François Collard; Mustapha Amyere; Gaëtane Noel; Jonathan Desmedt; Marie-Cécile Nassogne; Miikka Vikkula; Jean-Noël Octave; Marie-Françoise Vincent; Pierre J Courtoy; Eugen Boltshauser; Emile van Schaftingen
Journal:  Biochem J       Date:  2009-12-14       Impact factor: 3.857
  6 in total
  2 in total

1.  Increasing N-acetylaspartate in the Brain during Postnatal Myelination Does Not Cause the CNS Pathologies of Canavan Disease.

Authors:  Abhilash P Appu; John R Moffett; Peethambaran Arun; Sean Moran; Vikram Nambiar; Jishnu K S Krishnan; Narayanan Puthillathu; Aryan M A Namboodiri
Journal:  Front Mol Neurosci       Date:  2017-06-02       Impact factor: 5.639

2.  Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs.

Authors:  Lizhao Feng; Jianfei Chao; E Tian; Li Li; Peng Ye; Mi Zhang; Xianwei Chen; Qi Cui; Guihua Sun; Tao Zhou; Gerardo Felix; Yue Qin; Wendong Li; Edward David Meza; Jeremy Klein; Lucy Ghoda; Weidong Hu; Yonglun Luo; Wei Dang; David Hsu; Joseph Gold; Steven A Goldman; Reuben Matalon; Yanhong Shi
Journal:  Adv Sci (Weinh)       Date:  2020-10-29       Impact factor: 16.806
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.