| Literature DB >> 11310630 |
E Martin1, A Capone, J Schneider, J Hennig, T Thiel.
Abstract
N-acetylaspartate (NAA) contributes to the most prominent signal in proton magnetic resonance spectroscopy (1H-MRS) of the adult human brain. We report the absence of NAA in the brain of a 3-year-old child with neurodevelopmental retardation and moderately delayed myelination. Since normal concentration of NAA in body fluids is hardly detectable, 1H-MRS is a noninvasive technique for identifying neurometabolic diseases with absent NAA. This report puts NAA as a neuronal marker to question.Entities:
Mesh：
Substances：
Year: 2001 PMID： 11310630
Source DB: PubMed Journal: Ann Neurol ISSN： 0364-5134 Impact factor: 10.422