Literature DB >> 28373166

Exploring the Link between the Germline and Somatic Genome in Cancer.

Paul Geeleher1, R Stephanie Huang2.   

Abstract

<b/> Carter and colleagues propose a systematic analysis of the germline and somatic genome in cancer. They identify interactions that occur between germline and somatic variants. This elucidates the function of the germline genome in the context of cancer risk and development. Cancer Discov; 7(4); 354-5. ©2017 AACRSee related article by Carter et al., p. 410. ©2017 American Association for Cancer Research.

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Year:  2017        PMID： 28373166      PMCID： PMC5404740          DOI： 10.1158/2159-8290.CD-17-0192

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  10 in total

1.  Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.

Authors:  Siddhartha P Kar; Jonathan Beesley; Ali Amin Al Olama; Kyriaki Michailidou; Jonathan Tyrer; ZSofia Kote-Jarai; Kate Lawrenson; Sara Lindstrom; Susan J Ramus; Deborah J Thompson; Adam S Kibel; Agnieszka Dansonka-Mieszkowska; Agnieszka Michael; Aida K Dieffenbach; Aleksandra Gentry-Maharaj; Alice S Whittemore; Alicja Wolk; Alvaro Monteiro; Ana Peixoto; Andrzej Kierzek; Angela Cox; Anja Rudolph; Anna Gonzalez-Neira; Anna H Wu; Annika Lindblom; Anthony Swerdlow; Argyrios Ziogas; Arif B Ekici; Barbara Burwinkel; Beth Y Karlan; Børge G Nordestgaard; Carl Blomqvist; Catherine Phelan; Catriona McLean; Celeste Leigh Pearce; Celine Vachon; Cezary Cybulski; Chavdar Slavov; Christa Stegmaier; Christiane Maier; Christine B Ambrosone; Claus K Høgdall; Craig C Teerlink; Daehee Kang; Daniel C Tessier; Daniel J Schaid; Daniel O Stram; Daniel W Cramer; David E Neal; Diana Eccles; Dieter Flesch-Janys; Digna R Velez Edwards; Dominika Wokozorczyk; Douglas A Levine; Drakoulis Yannoukakos; Elinor J Sawyer; Elisa V Bandera; Elizabeth M Poole; Ellen L Goode; Elza Khusnutdinova; Estrid Høgdall; Fengju Song; Fiona Bruinsma; Florian Heitz; Francesmary Modugno; Freddie C Hamdy; Fredrik Wiklund; Graham G Giles; Håkan Olsson; Hans Wildiers; Hans-Ulrich Ulmer; Hardev Pandha; Harvey A Risch; Hatef Darabi; Helga B Salvesen; Heli Nevanlinna; Henrik Gronberg; Hermann Brenner; Hiltrud Brauch; Hoda Anton-Culver; Honglin Song; Hui-Yi Lim; Iain McNeish; Ian Campbell; Ignace Vergote; Jacek Gronwald; Jan Lubiński; Janet L Stanford; Javier Benítez; Jennifer A Doherty; Jennifer B Permuth; Jenny Chang-Claude; Jenny L Donovan; Joe Dennis; Joellen M Schildkraut; Johanna Schleutker; John L Hopper; Jolanta Kupryjanczyk; Jong Y Park; Jonine Figueroa; Judith A Clements; Julia A Knight; Julian Peto; Julie M Cunningham; Julio Pow-Sang; Jyotsna Batra; Kamila Czene; Karen H Lu; Kathleen Herkommer; Kay-Tee Khaw; Keitaro Matsuo; Kenneth Muir; Kenneth Offitt; Kexin Chen; Kirsten B Moysich; Kristiina Aittomäki; Kunle Odunsi; Lambertus A Kiemeney; Leon F A G Massuger; Liesel M Fitzgerald; Linda S Cook; Lisa Cannon-Albright; Maartje J Hooning; Malcolm C Pike; Manjeet K Bolla; Manuel Luedeke; Manuel R Teixeira; Marc T Goodman; Marjanka K Schmidt; Marjorie Riggan; Markus Aly; Mary Anne Rossing; Matthias W Beckmann; Matthieu Moisse; Maureen Sanderson; Melissa C Southey; Michael Jones; Michael Lush; Michelle A T Hildebrandt; Ming-Feng Hou; Minouk J Schoemaker; Montserrat Garcia-Closas; Natalia Bogdanova; Nazneen Rahman; Nhu D Le; Nick Orr; Nicolas Wentzensen; Nora Pashayan; Paolo Peterlongo; Pascal Guénel; Paul Brennan; Paula Paulo; Penelope M Webb; Per Broberg; Peter A Fasching; Peter Devilee; Qin Wang; Qiuyin Cai; Qiyuan Li; Radka Kaneva; Ralf Butzow; Reidun Kristin Kopperud; Rita K Schmutzler; Robert A Stephenson; Robert J MacInnis; Robert N Hoover; Robert Winqvist; Roberta Ness; Roger L Milne; Ruth C Travis; Sara Benlloch; Sara H Olson; Shannon K McDonnell; Shelley S Tworoger; Sofia Maia; Sonja Berndt; Soo Chin Lee; Soo-Hwang Teo; Stephen N Thibodeau; Stig E Bojesen; Susan M Gapstur; Susanne Krüger Kjær; Tanja Pejovic; Teuvo L J Tammela; Thilo Dörk; Thomas Brüning; Tiina Wahlfors; Tim J Key; Todd L Edwards; Usha Menon; Ute Hamann; Vanio Mitev; Veli-Matti Kosma; Veronica Wendy Setiawan; Vessela Kristensen; Volker Arndt; Walther Vogel; Wei Zheng; Weiva Sieh; William J Blot; Wojciech Kluzniak; Xiao-Ou Shu; Yu-Tang Gao; Fredrick Schumacher; Matthew L Freedman; Andrew Berchuck; Alison M Dunning; Jacques Simard; Christopher A Haiman; Amanda Spurdle; Thomas A Sellers; David J Hunter; Brian E Henderson; Peter Kraft; Stephen J Chanock; Fergus J Couch; Per Hall; Simon A Gayther; Douglas F Easton; Georgia Chenevix-Trench; Rosalind Eeles; Paul D P Pharoah; Diether Lambrechts
Journal:  Cancer Discov       Date:  2016-07-17       Impact factor: 39.397

2.  A systematic review of cancer GWAS and candidate gene meta-analyses reveals limited overlap but similar effect sizes.

Authors:  Christine Q Chang; Ajay Yesupriya; Jessica L Rowell; Camilla B Pimentel; Melinda Clyne; Marta Gwinn; Muin J Khoury; Anja Wulf; Sheri D Schully
Journal:  Eur J Hum Genet       Date:  2013-07-24       Impact factor: 4.246

3.  Interaction Landscape of Inherited Polymorphisms with Somatic Events in Cancer.

Authors:  Hannah Carter; Rachel Marty; Matan Hofree; Andrew M Gross; James Jensen; Kathleen M Fisch; Xingyu Wu; Christopher DeBoever; Eric L Van Nostrand; Yan Song; Emily Wheeler; Jason F Kreisberg; Scott M Lippman; Gene W Yeo; J Silvio Gutkind; Trey Ideker
Journal:  Cancer Discov       Date:  2017-02-10       Impact factor: 39.397

Review 4.  Pharmacogenomics in the clinic.

Authors:  Mary V Relling; William E Evans
Journal:  Nature       Date:  2015-10-15       Impact factor: 49.962

5.  Linkage of early-onset familial breast cancer to chromosome 17q21.

Authors:  J M Hall; M K Lee; B Newman; J E Morrow; L A Anderson; B Huey; M C King
Journal:  Science       Date:  1990-12-21       Impact factor: 47.728

Review 6.  Integrative eQTL-based analyses reveal the biology of breast cancer risk loci.

Authors:  Qiyuan Li; Ji-Heui Seo; Barbara Stranger; Aaron McKenna; Itsik Pe'er; Thomas Laframboise; Myles Brown; Svitlana Tyekucheva; Matthew L Freedman
Journal:  Cell       Date:  2013-01-31       Impact factor: 41.582

7.  Putative cis-regulatory drivers in colorectal cancer.

Authors:  Halit Ongen; Claus L Andersen; Jesper B Bramsen; Bodil Oster; Mads H Rasmussen; Pedro G Ferreira; Juan Sandoval; Enrique Vidal; Nicola Whiffin; Alexandra Planchon; Ismael Padioleau; Deborah Bielser; Luciana Romano; Ian Tomlinson; Richard S Houlston; Manel Esteller; Torben F Orntoft; Emmanouil T Dermitzakis
Journal:  Nature       Date:  2014-07-23       Impact factor: 49.962

8.  Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.

Authors:  Kyriaki Michailidou; Jonathan Beesley; Sara Lindstrom; Sander Canisius; Joe Dennis; Michael J Lush; Mel J Maranian; Manjeet K Bolla; Qin Wang; Mitul Shah; Barbara J Perkins; Kamila Czene; Mikael Eriksson; Hatef Darabi; Judith S Brand; Stig E Bojesen; Børge G Nordestgaard; Henrik Flyger; Sune F Nielsen; Nazneen Rahman; Clare Turnbull; Olivia Fletcher; Julian Peto; Lorna Gibson; Isabel dos-Santos-Silva; Jenny Chang-Claude; Dieter Flesch-Janys; Anja Rudolph; Ursula Eilber; Sabine Behrens; Heli Nevanlinna; Taru A Muranen; Kristiina Aittomäki; Carl Blomqvist; Sofia Khan; Kirsimari Aaltonen; Habibul Ahsan; Muhammad G Kibriya; Alice S Whittemore; Esther M John; Kathleen E Malone; Marilie D Gammon; Regina M Santella; Giske Ursin; Enes Makalic; Daniel F Schmidt; Graham Casey; David J Hunter; Susan M Gapstur; Mia M Gaudet; W Ryan Diver; Christopher A Haiman; Fredrick Schumacher; Brian E Henderson; Loic Le Marchand; Christine D Berg; Stephen J Chanock; Jonine Figueroa; Robert N Hoover; Diether Lambrechts; Patrick Neven; Hans Wildiers; Erik van Limbergen; Marjanka K Schmidt; Annegien Broeks; Senno Verhoef; Sten Cornelissen; Fergus J Couch; Janet E Olson; Emily Hallberg; Celine Vachon; Quinten Waisfisz; Hanne Meijers-Heijboer; Muriel A Adank; Rob B van der Luijt; Jingmei Li; Jianjun Liu; Keith Humphreys; Daehee Kang; Ji-Yeob Choi; Sue K Park; Keun-Young Yoo; Keitaro Matsuo; Hidemi Ito; Hiroji Iwata; Kazuo Tajima; Pascal Guénel; Thérèse Truong; Claire Mulot; Marie Sanchez; Barbara Burwinkel; Frederik Marme; Harald Surowy; Christof Sohn; Anna H Wu; Chiu-chen Tseng; David Van Den Berg; Daniel O Stram; Anna González-Neira; Javier Benitez; M Pilar Zamora; Jose Ignacio Arias Perez; Xiao-Ou Shu; Wei Lu; Yu-Tang Gao; Hui Cai; Angela Cox; Simon S Cross; Malcolm W R Reed; Irene L Andrulis; Julia A Knight; Gord Glendon; Anna Marie Mulligan; Elinor J Sawyer; Ian Tomlinson; Michael J Kerin; Nicola Miller; Annika Lindblom; Sara Margolin; Soo Hwang Teo; Cheng Har Yip; Nur Aishah Mohd Taib; Gie-Hooi Tan; Maartje J Hooning; Antoinette Hollestelle; John W M Martens; J Margriet Collée; William Blot; Lisa B Signorello; Qiuyin Cai; John L Hopper; Melissa C Southey; Helen Tsimiklis; Carmel Apicella; Chen-Yang Shen; Chia-Ni Hsiung; Pei-Ei Wu; Ming-Feng Hou; Vessela N Kristensen; Silje Nord; Grethe I Grenaker Alnaes; Graham G Giles; Roger L Milne; Catriona McLean; Federico Canzian; Dimitrios Trichopoulos; Petra Peeters; Eiliv Lund; Malin Sund; Kay-Tee Khaw; Marc J Gunter; Domenico Palli; Lotte Maxild Mortensen; Laure Dossus; Jose-Maria Huerta; Alfons Meindl; Rita K Schmutzler; Christian Sutter; Rongxi Yang; Kenneth Muir; Artitaya Lophatananon; Sarah Stewart-Brown; Pornthep Siriwanarangsan; Mikael Hartman; Hui Miao; Kee Seng Chia; Ching Wan Chan; Peter A Fasching; Alexander Hein; Matthias W Beckmann; Lothar Haeberle; Hermann Brenner; Aida Karina Dieffenbach; Volker Arndt; Christa Stegmaier; Alan Ashworth; Nick Orr; Minouk J Schoemaker; Anthony J Swerdlow; Louise Brinton; Montserrat Garcia-Closas; Wei Zheng; Sandra L Halverson; Martha Shrubsole; Jirong Long; Mark S Goldberg; France Labrèche; Martine Dumont; Robert Winqvist; Katri Pylkäs; Arja Jukkola-Vuorinen; Mervi Grip; Hiltrud Brauch; Ute Hamann; Thomas Brüning; Paolo Radice; Paolo Peterlongo; Siranoush Manoukian; Loris Bernard; Natalia V Bogdanova; Thilo Dörk; Arto Mannermaa; Vesa Kataja; Veli-Matti Kosma; Jaana M Hartikainen; Peter Devilee; Robert A E M Tollenaar; Caroline Seynaeve; Christi J Van Asperen; Anna Jakubowska; Jan Lubinski; Katarzyna Jaworska; Tomasz Huzarski; Suleeporn Sangrajrang; Valerie Gaborieau; Paul Brennan; James McKay; Susan Slager; Amanda E Toland; Christine B Ambrosone; Drakoulis Yannoukakos; Maria Kabisch; Diana Torres; Susan L Neuhausen; Hoda Anton-Culver; Craig Luccarini; Caroline Baynes; Shahana Ahmed; Catherine S Healey; Daniel C Tessier; Daniel Vincent; Francois Bacot; Guillermo Pita; M Rosario Alonso; Nuria Álvarez; Daniel Herrero; Jacques Simard; Paul P D P Pharoah; Peter Kraft; Alison M Dunning; Georgia Chenevix-Trench; Per Hall; Douglas F Easton
Journal:  Nat Genet       Date:  2015-03-09       Impact factor: 38.330

9.  Obesity-associated variants within FTO form long-range functional connections with IRX3.

Authors:  Scott Smemo; Juan J Tena; Kyoung-Han Kim; Eric R Gamazon; Noboru J Sakabe; Carlos Gómez-Marín; Ivy Aneas; Flavia L Credidio; Débora R Sobreira; Nora F Wasserman; Ju Hee Lee; Vijitha Puviindran; Davis Tam; Michael Shen; Joe Eun Son; Niki Alizadeh Vakili; Hoon-Ki Sung; Silvia Naranjo; Rafael D Acemel; Miguel Manzanares; Andras Nagy; Nancy J Cox; Chi-Chung Hui; Jose Luis Gomez-Skarmeta; Marcelo A Nóbrega
Journal:  Nature       Date:  2014-03-12       Impact factor: 49.962

10.  Utility of patient-derived lymphoblastoid cell lines as an ex vivo capecitabine sensitivity prediction model for breast cancer patients.

Authors:  Gladys Morrison; Divya Lenkala; Bonnie LaCroix; Dana Ziliak; Vandana Abramson; Phuong Khanh Morrow; Andres Forero; Catherine Van Poznak; Hope S Rugo; Rita Nanda; Peter H O'Donnell; R Stephanie Huang
Journal:  Oncotarget       Date:  2016-06-21
  10 in total
  3 in total

1.  Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology.

Authors:  Muktar Ahmed; Ville-Petteri Mäkinen; Anwar Mulugeta; Jisu Shin; Terry Boyle; Elina Hyppönen; Sang Hong Lee
Journal:  Commun Biol       Date:  2022-06-21

Review 2.  Germline Risk Contribution to Genomic Instability in Multiple Myeloma.

Authors:  Siegfried Janz; Fenghuang Zhan; Fumou Sun; Yan Cheng; Michael Pisano; Ye Yang; Hartmut Goldschmidt; Parameswaran Hari
Journal:  Front Genet       Date:  2019-05-08       Impact factor: 4.599

3.  Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity.

Authors:  Paul Geeleher; Aritro Nath; Fan Wang; Zhenyu Zhang; Alvaro N Barbeira; Jessica Fessler; Robert L Grossman; Cathal Seoighe; R Stephanie Huang
Journal:  Genome Biol       Date:  2018-09-11       Impact factor: 13.583
  3 in total

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