Literature DB >> 2837267

Alpha-1-antitrypsin hepatic cell globules in autotransplanted liver of rats.

A P Jayaraj1.   

Abstract

The autotransplantation of liver into the subcutaneous tissues in rats and hamsters resulted in the development of periodic acid Schiffs staining positive granules, which were resistant to diastase digestion. These granules were confirmed as alpha-1-antitrypsin by immunohistochemical staining. The appearance of the alpha-1-antitrypsin containing hepatic granules is comparable to those seen in the liver of humans with genetically determined alpha-1-antitrypsin deficiency.

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Year:  1988        PMID： 2837267      PMCID： PMC2013218     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  5 in total

1.  HETEROTOPIC PARTIAL AUTOTRANSPLANTATION OF RAT LIVER: TECHNIC AND DEMONSTRATION OF STRUCTURE AND FUNCTION OF THE GRAFT.

Authors:  J W GRISHAM; G F LEONG; B V HOLE
Journal:  Cancer Res       Date:  1964-09       Impact factor: 12.701

2.  Autotransplantation of liver: description of a method.

Authors:  B SIGEL; I M POTASH; J H MEDLIN; M W WOLCOTT
Journal:  Surgery       Date:  1960-06       Impact factor: 3.982

3.  Isolation and characterization of alpha 1-antitrypsin in PAS-positive hepatic granules from rats with experimental alpha 1-antitrypsin deficiency.

Authors:  S Bolmer; J Kleinerman
Journal:  Am J Pathol       Date:  1986-05       Impact factor: 4.307

4.  Cirrhosis associated with alpha-1-antitrypsin deficiency: a previously unrecognized inherited disorder.

Authors:  H L Sharp; R A Bridges; W Krivit; E F Freier
Journal:  J Lab Clin Med       Date:  1969-06

5.  Ultrastructural liver pathology in patients with minimal liver disease and alpha 1-antitrypsin deficiency: a comparison between heterozygous and homozygous patients.

Authors:  R Hultcrantz; S Mengarelli
Journal:  Hepatology       Date:  1984 Sep-Oct       Impact factor: 17.425
  5 in total

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