Literature DB >> 28358709

Lack of Definite Association of Vitamin D Deficiency with Diabetic Neuropathy. Investigation in Greek and in Bangladeshi Patients.

Thomas Zambelis1, George Papadakis2, Panagiotis Kokotis3, Vassiliki Villiotou4, Nikolaos Dogkas4, Nikolaos Karandreas3.   

Abstract

AIM: Determination of the 25(OH) vitamin D levels in Greek-born and in Bangladeshi immigrant patients in Greece with diabetes with and without polyneuropathy.
MATERIALS AND METHODS: The method for the detection and staging of polyneuropathy proposed by Dyck, 1988 was used.
RESULTS: A total of 111 Bangladeshi immigrants and 101 Greek diabetic patients took part in the study. Vitamin D levels were significantly lower in Bangladeshi than in Greek diabetic patients, and were significantly lower in Greek patients with small-fiber neuropathy. In Bangladeshi patients, there was no statistically significant difference in the subgroup of patients with polyneuropathy in comparison to those without polyneuropathy.
CONCLUSION: The association of vitamin D deficiency only with a small number of Greek patients with exclusively small-fiber neuropathy does not allow us to draw a definite conclusion on the role of vitamin D in the pathogenesis of diabetic neuropathy. Copyright
© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Bangladeshi; Diabetic neuropathy; Greek; vitamin D

Mesh:

Substances:

Year:  2017        PMID: 28358709      PMCID: PMC5411754          DOI: 10.21873/invivo.11054

Source DB:  PubMed          Journal:  In Vivo        ISSN: 0258-851X            Impact factor:   2.155


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