Literature DB >> 28348634

Trans-synaptic Retrograde Degeneration Following Hemispherectomy in Childhood.

Sian E Handley1, Vasiliki S Panteli1, Alki Liasis1.   

Abstract

Trans-synaptic retrograde degeneration (TRD) in the human visual system has been established. However there are few studies demonstrating macular thinning of the Retinal Ganglion cell Layer and/or Inner Plexiform layer (RGCL-IPL), corresponding to an acquired homonymous hemianopia. We report a 17 year old with a homonymous hemianopia, secondary to a hemispherectomy for intractable epilepsy. Three years following hemispherectomy, Optical Coherence Tomography (OCT) revealed evidence of TRD, corresponding to his complete homonymous hemianopia. Macular maps of the RGCL-IPL thickness provides useful additional information to measurements of optic nerve Retinal Nerve Fibre Layer Thickness (RNFL) in identifying TRD in acquired homonymous hemianopia.

Entities:  

Keywords:  Hemispherectomy; homonymous hemianopia; inner plexiform layer; optical coherence tomography; retinal ganglion cell layer; trans-synaptic retrograde degeneration

Year:  2017        PMID： 28348634      PMCID： PMC5354094          DOI： 10.1080/01658107.2016.1276935

Source DB:  PubMed          Journal:  Neuroophthalmology        ISSN： 0165-8107


  13 in total

1.  Transneuronal degeneration of retinal ganglion cells in early hemispherectomized monkeys.

Authors:  M Herbin; D Boire; H Théoret; M Ptito
Journal:  Neuroreport       Date:  1999-05-14       Impact factor: 1.837

2.  TRANS-SYNAPTIC RETROGRADE DEGENERATION IN THE VISUAL SYSTEM OF PRIMATES.

Authors:  J M VANBUREN
Journal:  J Neurol Neurosurg Psychiatry       Date:  1963-10       Impact factor: 10.154

3.  Homonymous hemioptic hypoplasia. Fundoscopic features in standard and red-free illumination in three patients with congenital hemiplegia.

Authors:  W F Hoyt; E N Rios-Montenegro; M M Behrens; R J Eckelhoff
Journal:  Br J Ophthalmol       Date:  1972-07       Impact factor: 4.638

4.  Retrograde trans-synaptic retinal ganglion cell loss identified by optical coherence tomography.

Authors:  Panitha Jindahra; Aviva Petrie; Gordon T Plant
Journal:  Brain       Date:  2009-02-18       Impact factor: 13.501

5.  Transneuronal retrograde degeneration of the retinal ganglion cells in patients with cerebral infarction.

Authors:  Hae-Young Lopilly Park; Young Gun Park; A-Hyun Cho; Chan Kee Park
Journal:  Ophthalmology       Date:  2013-02-08       Impact factor: 12.079

6.  Quantifying the pattern of optic tract degeneration in human hemianopia.

Authors:  Rebecca S Millington; Clarissa L Yasuda; Panitha Jindahra; Mark Jenkinson; John L Barbur; Christopher Kennard; Fernando Cendes; Gordon T Plant; Holly Bridge
Journal:  J Neurol Neurosurg Psychiatry       Date:  2013-10-25       Impact factor: 10.154

7.  Homonymous Ganglion Cell Layer Thinning After Isolated Occipital Lesion: Macular OCT Demonstrates Transsynaptic Retrograde Retinal Degeneration.

Authors:  Paolo G Meier; Philippe Maeder; Randy H Kardon; François-Xavier Borruat
Journal:  J Neuroophthalmol       Date:  2015-06       Impact factor: 3.042

8.  Retrograde degeneration of retinal ganglion cells in homonymous hemianopsia.

Authors:  Angela M Herro; Byron L Lam
Journal:  Clin Ophthalmol       Date:  2015-06-11

9.  Lesions in the posterior visual pathway promote trans-synaptic degeneration of retinal ganglion cells.

Authors:  Johannes Keller; Bernardo F Sánchez-Dalmau; Pablo Villoslada
Journal:  PLoS One       Date:  2014-05-23       Impact factor: 3.240

10.  Sectoral analysis of the retinal nerve fiber layer thinning and its association with visual field loss in homonymous hemianopia caused by post-geniculate lesions using spectral-domain optical coherence tomography.

Authors:  Katsutoshi Goto; Atsushi Miki; Tsutomu Yamashita; Syunsuke Araki; Go Takizawa; Masaki Nakagawa; Yoshiaki Ieki; Junichi Kiryu
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-10-07       Impact factor: 3.117
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