W H Salem1, A Abdullah2, O Abuzeid2, K Bendikson3, F I Sharara4, M Abuzeid2. 1. University of Southern California, 020 Zonal Ave, IRD Room 533, Los Angeles, CA, 90033, USA. salem.wael@gmail.com. 2. IVF Michigan, Rochester Hills/Flint MI, 3950 S Rochester Rd, Ste 2300, Rochester Hills, MI, 48307, USA. 3. University of Southern California, 020 Zonal Ave, IRD Room 533, Los Angeles, CA, 90033, USA. 4. Virginia Center for Reproductive Medicine, 11150 Sunset Hills Rd #100, Reston, VA, 20190, USA.
Abstract
PURPOSE: The objective of this study is to determine if IVF outcome disparities exist among MENA women in the USA in comparison to a control group of Caucasian women. METHODS: A retrospective cohort study comparing MENA (N = 190) and Caucasian (N = 200) women undergoing their first IVF cycle between 5/2006 and 5/2014 was carried out at an academically affiliated fertility practice. All MENA cycles during that time period undergoing IVF/ICSI using autologous embryos and blastocyst transfers were compared to a control group of Caucasian women. RESULTS: MENA women were significantly younger (32.9 vs 34.5, P < 0.005) and had a lower BMI (25.2 vs 27.1, P < 0.001). Male factor infertility was higher among partners of MENA women (62 vs 50%, P < 0.05). MENA women experienced decreased live birth rates per blastocyst transfer compared to Caucasian women after controlling for age and BMI (OR 0.55, 95% CI 0.35-0.85 P = 0.007). The odds of a miscarriage were also significantly higher among MENA women (OR 2.55, 95% CI 1.04-6.27 P = 0.036). CONCLUSION: Middle Eastern/North African women have worse IVF outcomes with decreased live birth rates per blastocyst transfer and increased miscarriage rates compared to Caucasian women.
PURPOSE: The objective of this study is to determine if IVF outcome disparities exist among MENAwomen in the USA in comparison to a control group of Caucasian women. METHODS: A retrospective cohort study comparing MENA (N = 190) and Caucasian (N = 200) women undergoing their first IVF cycle between 5/2006 and 5/2014 was carried out at an academically affiliated fertility practice. All MENA cycles during that time period undergoing IVF/ICSI using autologous embryos and blastocyst transfers were compared to a control group of Caucasian women. RESULTS:MENAwomen were significantly younger (32.9 vs 34.5, P < 0.005) and had a lower BMI (25.2 vs 27.1, P < 0.001). Male factor infertility was higher among partners of MENAwomen (62 vs 50%, P < 0.05). MENAwomen experienced decreased live birth rates per blastocyst transfer compared to Caucasian women after controlling for age and BMI (OR 0.55, 95% CI 0.35-0.85 P = 0.007). The odds of a miscarriage were also significantly higher among MENAwomen (OR 2.55, 95% CI 1.04-6.27 P = 0.036). CONCLUSION: Middle Eastern/North African women have worse IVF outcomes with decreased live birth rates per blastocyst transfer and increased miscarriage rates compared to Caucasian women.
Entities:
Keywords:
Arab American; Ethnicity; Health disparity; IVF; Race
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