Literature DB >> 2833683

Multiple sclerosis etiology--an Epstein-Barr virus hypothesis.

H B Warner1, R I Carp.   

Abstract

The opinion has been expressed frequently in the literature that MS is caused by a combination of an environmental agent and genetic factors, possibly with an autoimmune component. However, the specific environmental agent has not as yet been identified. This paper describes cumulative circumstantial evidence which strongly points to a post-pubertal primary Epstein-Barr virus infection as this unidentified etiological event in the induction of MS disease.

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Year:  1988        PMID： 2833683     DOI： 10.1016/0306-9877(88)90024-2

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN： 0306-9877            Impact factor:   1.538


  7 in total

1.  Epstein-Barr virus infection of human astrocyte cell lines.

Authors:  A Menet; C Speth; C Larcher; W M Prodinger; M G Schwendinger; P Chan; M Jäger; F Schwarzmann; H Recheis; M Fontaine; M P Dierich
Journal:  J Virol       Date:  1999-09       Impact factor: 5.103

Review 2.  Epstein-Barr virus in multiple sclerosis.

Authors:  Bridget A Bagert
Journal:  Curr Neurol Neurosci Rep       Date:  2009-09       Impact factor: 5.081

3.  XVI European Charcot Foundation lecture: nutrition and environment: can MS be prevented?

Authors:  Kelly Claire Simon; Kassandra L Munger; Alberto Ascherio
Journal:  J Neurol Sci       Date:  2011-10-04       Impact factor: 3.181

4.  Analysis of Micro-RNA-144 Expression Profile in Patients with Multiple Sclerosis in Comparison with Healthy Individuals.

Authors:  Fatemeh Roshani; Hossien Delavar Kasmaee; Kowsar Falahati; Ghazaleh Arabzade; Atefeh Sohan Forooshan Moghadam; Mohammad Hossein Sanati
Journal:  Rep Biochem Mol Biol       Date:  2021-10

5.  Clinical relapses and disease activity on magnetic resonance imaging associated with viral upper respiratory tract infections in multiple sclerosis.

Authors:  S Edwards; M Zvartau; H Clarke; W Irving; L D Blumhardt
Journal:  J Neurol Neurosurg Psychiatry       Date:  1998-06       Impact factor: 10.154

6.  Epigenetic Plasticity Enables CNS-Trafficking of EBV-infected B Lymphocytes.

Authors:  Samantha S Soldan; Chenhe Su; R Jason Lamontagne; Nicholas Grams; Fang Lu; Yue Zhang; James D Gesualdi; Drew M Frase; Lois E Tolvinski; Kayla Martin; Troy E Messick; Jonathan T Fingerut; Ekaterina Koltsova; Andrew Kossenkov; Paul M Lieberman
Journal:  PLoS Pathog       Date:  2021-06-09       Impact factor: 6.823

Review 7.  The CD8 T Cell-Epstein-Barr Virus-B Cell Trialogue: A Central Issue in Multiple Sclerosis Pathogenesis.

Authors:  Caterina Veroni; Francesca Aloisi
Journal:  Front Immunol       Date:  2021-07-07       Impact factor: 7.561
  7 in total

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