Literature DB >> 28334132

Maximum likelihood estimation and EM algorithm of Copas-like selection model for publication bias correction.

Jing Ning1, Yong Chen2, Jin Piao3.   

Abstract

Publication bias occurs when the published research results are systematically unrepresentative of the population of studies that have been conducted, and is a potential threat to meaningful meta-analysis. The Copas selection model provides a flexible framework for correcting estimates and offers considerable insight into the publication bias. However, maximizing the observed likelihood under the Copas selection model is challenging because the observed data contain very little information on the latent variable. In this article, we study a Copas-like selection model and propose an expectation-maximization (EM) algorithm for estimation based on the full likelihood. Empirical simulation studies show that the EM algorithm and its associated inferential procedure performs well and avoids the non-convergence problem when maximizing the observed likelihood.
© The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Keywords:  Copas Model; EM algorithm; Meta-analysis; Publication Bias

Mesh:

Year:  2017        PMID: 28334132      PMCID: PMC5862358          DOI: 10.1093/biostatistics/kxx004

Source DB:  PubMed          Journal:  Biostatistics        ISSN: 1465-4644            Impact factor:   5.899


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