| Literature DB >> 28331826 |
Jian-Wei Gao1, Stefania Rizzo2, Li-Hong Ma1, Xiang-Yu Qiu3, Arne Warth4, Nobuhiko Seki5, Mizue Hasegawa6, Jia-Wei Zou1, Qian Li1, Marco Femia7, Tang-Feng Lv1, Yong Song1.
Abstract
The incidence of pulmonary ground-glass opacity (GGO) lesions is increasing as a result of the widespread use of multislice spiral computed tomography (CT) and the low-dose CT screening for lung cancer detection. Besides benign lesions, GGOs can be a specific type of lung adenocarcinomas or their preinvasive lesions. Evaluation of pulmonary GGO and investigation of the correlation between CT imaging features and lung adenocarcinoma subtypes or driver genes can be helpful in confirming the diagnosis and in guiding the clinical management. Our review focuses on the pathologic characteristics of GGO detected at CT, involving histopathology and molecular pathology.Entities:
Keywords: Ground-glass opacity (GGO); Kirsten rat sarcoma viral oncogene homolog (KRAS); anaplastic lymphoma kinase gene (ALK); computed tomography (CT); driver genes; epidermal growth factor receptor gene (EGFR); pathology
Year: 2017 PMID： 28331826 PMCID： PMC5344841 DOI： 10.21037/tlcr.2017.01.02
Source DB: PubMed Journal: Transl Lung Cancer Res ISSN： 2218-6751