Mariam Ter-Stepanian1, Natalie Grizenko2, Kim Cornish3, Victoria Talwar4, Valentin Mbekou5, Norbert Schmitz6, Ridha Joober2. 1. ADHD Clinic, Douglas Mental Health University Institute, Montreal, Quebec. 2. Child and Adolescent Psychiatry Program, Douglas Mental Health University Institute, Montreal, Quebec; Department of Psychiatry, McGill University, Montreal, Quebec. 3. Centre for Developmental Psychiatry & Psychology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia. 4. Department of Educational and Counselling Psychology, McGill University, Montreal, Quebec. 5. Child and Adolescent Psychiatry Program, Douglas Mental Health University Institute, Montreal, Quebec. 6. Douglas Mental Health University Institute Research Centre, Montreal, Quebec.
Abstract
OBJECTIVE: The goal of this study was to examine the relationship between comorbid disorders and executive function (EF) in children diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD). METHODS: Three hundred and fifty-five, 6-12 year old children clinically diagnosed with ADHD were included in the study. Comorbid anxiety disorders, Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD) were examined. The EF domains were assessed using the Conners' Continuous Performance Test (CPT), Wisconsin Card Sorting Test (WCST), Tower of London (ToL), Finger Windows (FW) and Self Ordered Pointing Test (SOPT). RESULTS: The findings indicate that children with comorbid anxiety disorders performed worse in domains measured by CPT and prior to controlling for age and sex, by FW. However, once sex was controlled for the results for FW were no longer significant. Children with CD obtained lower scores on WCST. Furthermore, a significant sex by CD interaction was observed. CONCLUSION: These results indicate that comorbid disorders should be carefully examined as they play a significant role in EF performance and subsequently in day-to-day functioning of children with ADHD.
OBJECTIVE: The goal of this study was to examine the relationship between comorbid disorders and executive function (EF) in children diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD). METHODS: Three hundred and fifty-five, 6-12 year old children clinically diagnosed with ADHD were included in the study. Comorbid anxiety disorders, Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD) were examined. The EF domains were assessed using the Conners' Continuous Performance Test (CPT), Wisconsin Card Sorting Test (WCST), Tower of London (ToL), Finger Windows (FW) and Self Ordered Pointing Test (SOPT). RESULTS: The findings indicate that children with comorbid anxiety disorders performed worse in domains measured by CPT and prior to controlling for age and sex, by FW. However, once sex was controlled for the results for FW were no longer significant. Children with CD obtained lower scores on WCST. Furthermore, a significant sex by CD interaction was observed. CONCLUSION: These results indicate that comorbid disorders should be carefully examined as they play a significant role in EF performance and subsequently in day-to-day functioning of children with ADHD.
Authors: Jessica W O'Brien; Lauren R Dowell; Stewart H Mostofsky; Martha B Denckla; E Mark Mahone Journal: Arch Clin Neuropsychol Date: 2010-07-16 Impact factor: 2.813