Literature DB >> 2832321

Absence of antiviral activity in recombinant B cell stimulatory factor 2 (BSF-2).

T Hirano1, T Matsuda, K Hosoi, A Okano, H Matsui, T Kishimoto.   

Abstract

Recombinant B cell stimulatory factor 2 (rBSF-2) did not display any detectable level of antiviral activity when using human diploid fibroblasts, DIP-2, FS-4, FS-7, amnion-derived WISH and FL cells with vesicular stomatitis virus (VSV) and Sindbis virus as challenging agents (less than 2.5 X 10(2) IU/mg). Furthermore anti-IFN-beta could not neutralize the immunoglobulin-inducing activity of BSF-2. Moreover anti-BSF-2 could not neutralize the antiviral activity of IFN-beta. The data indicate that BSF-2 is functionally and immunologically not related to IFNs.

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Year:  1988        PMID： 2832321     DOI： 10.1016/0165-2478(88)90099-5

Source DB:  PubMed          Journal:  Immunol Lett        ISSN： 0165-2478            Impact factor:   3.685


  16 in total

1.  A critical role of the transcription factor fli-1 in murine lupus development by regulation of interleukin-6 expression.

Authors:  Shuzo Sato; Mara Lennard Richard; Danielle Brandon; Joy N Jones Buie; Jim C Oates; Gary S Gilkeson; Xian K Zhang
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Review 2.  Interleukin-6 and the acute phase response.

Authors:  P C Heinrich; J V Castell; T Andus
Journal:  Biochem J       Date:  1990-02-01       Impact factor: 3.857

3.  Immunologic abnormality in NZB/W F1 mice. Thymus-independent expansion of B cells responding to interleukin-6.

Authors:  M Mihara; H Fukui; Y Koishihara; M Saito; Y Ohsugi
Journal:  Clin Exp Immunol       Date:  1990-12       Impact factor: 4.330

4.  Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6.

Authors:  T Satoh; S Nakamura; T Taga; T Matsuda; T Hirano; T Kishimoto; Y Kaziro
Journal:  Mol Cell Biol       Date:  1988-08       Impact factor: 4.272

5.  Signal delivery by physical interaction and soluble factors from accessory cells in the induction of receptor-mediated T-cell proliferation. Synergistic effect of BSF-2/IL-6 and IL-1.

Authors:  K Kawakami; K Kakimoto; T Shinbori; K Onoue
Journal:  Immunology       Date:  1989-07       Impact factor: 7.397

Review 6.  IL-6: from laboratory to bedside.

Authors:  Tadamitsu Kishimoto
Journal:  Clin Rev Allergy Immunol       Date:  2005-06       Impact factor: 8.667

7.  Interleukin 2-dependent and interleukin 2-independent pathways of regulation of thymocyte function by interleukin 6.

Authors:  J M Le; G Fredrickson; L F Reis; T Diamantstein; T Hirano; T Kishimoto; J Vilcek
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

8.  Cytokine expression in synovial membranes of patients with rheumatoid arthritis and osteoarthritis.

Authors:  M N Farahat; G Yanni; R Poston; G S Panayi
Journal:  Ann Rheum Dis       Date:  1993-12       Impact factor: 19.103

9.  Intramuscular gold decreases cytokine expression and macrophage numbers in the rheumatoid synovial membrane.

Authors:  G Yanni; M Nabil; M R Farahat; R N Poston; G S Panayi
Journal:  Ann Rheum Dis       Date:  1994-05       Impact factor: 19.103

10.  Contrasting levels of in vitro cytokine production by rheumatoid synovial tissues demonstrating different patterns of mononuclear cell infiltration.

Authors:  G Yanni; A Whelan; C Feighery; W Quinlan; J Symons; G Duff; B Bresnihan
Journal:  Clin Exp Immunol       Date:  1993-09       Impact factor: 4.330
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